Factores de riesgo cardiometabólico y funcionamiento cognitivo: el rol de la reserva cognitiva

Primer Autor
Cancino, Margarita
Co-autores
Sepulveda-Pezoa, Luciana
Gomez-Perez, Daniela
Ortiz, Manuel S.
Salinas-Rehbein, Belen
Título
Factores de riesgo cardiometabólico y funcionamiento cognitivo: el rol de la reserva cognitiva
Editorial
SOC MEDICA SANTIAGO
Revista
REVISTA MEDICA DE CHILE
Lenguaje
es
Resumen
Background: Several risk factors are associated with cognitive impairment in older people, but little attention has been paid to cardiometabolic variables, as well as how cognitive reserve can mediate this association. Aim: To determine the association of cardiometabolic risk factors with cognitive functioning and whether the cognitive reserve mediates this association. Material and Methods: A cross-sectional study with 300 participants with a median age of 56 years (53% male) was conducted. Participants had a cognitive functioning assessment. Fasting glucose, HDL-cholesterol, and blood pressure were measured Results: A Structural Equation Modeling, revealed a direct effect of cardiometabolic latent risk factors on both a cognitive functioning (beta = -.204, p = .056), and cognitive reserve factors (beta = -.236, p = .04). Cognitive reserve was directly associated with cognitive functioning (beta = .327, p = .01), but did not mediate the association between the cardiometabolic risk factors and cognitive functioning (beta = .077, p= .07). The overall goodness of fitness was excellent chi(2) ( 50) = 58.357, p = .195, comparative fit index = .980, Tucker-Lewis Index = .974, root mean square error of approximation = .023 and Standardized Root Mean Square Residual = .041. Conclusions A direct effect of cardiometabolic risk factors on cognitive functioning was observed.
Tipo de Recurso
artículo original
doi
10.4067/s0034-98872021000801134
Formato Recurso
PDF
Palabras Claves
Aging
Cardiometabolic Risk Factors
Cognition
Cognitive Reserve
DELAYED CUED-RECALL
OLDER-ADULTS
HDL-CHOLESTEROL
WORKING-MEMORY
ATHEROSCLEROSIS
HYPERTENSION
POPULATION
IMMEDIATE
MIDLIFE
RESERVE
Ubicación del archivo
http://dx.doi.org/10.4067/s0034-98872021000801134
Categoría OCDE
Medicina general e interna
Materias
Envejecimiento
Factores de riesgo cardiometabólico
Cognición
Reserva cognitiva
RECUERDO RETARDADO
ADULTOS MAYORES
COLESTEROL-HDL
MEMORIA-TRABAJADORA
ATEROSCLEROSIS
HIPERTENSIÓN
POBLACIÓN
INMEDIATA
MEDIDA VIDA
RESERVA
Disciplinas de la OCDE
Neurociencias
Endocrinología y Metabolismo (Incluye Diabetes, Hormonas)
Otros Temas de Medicina Básica
Título de la cita (Recomendado-único)
Factores de riesgo cardiometabólico y funcionamiento cognitivo: el rol de la reserva cognitiva
Página de inicio (Recomendado-único)
1134
Página final (Recomendado-único)
1140
Identificador del recurso (Mandatado-único)
artículo original
Versión del recurso (Recomendado-único)
version publicada
License
CC BY 4.0
Condición de la licencia (Recomendado-repetible)
CC BY 4.0
Derechos de acceso
acceso abierto
Access Rights
acceso abierto
Id de Web of Science
WOS:000733663600004
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