Repositorio UFRO · Omeka S

Effectiveness of Copper Nanoparticles in Wound Healing Process Using In Vivo and In Vitro Studies: A Systematic Review

Primer Autor	Sandoval, Cristian
Co-autores	Rios, Gemima Sepulveda, Natalia Salvo, Jessica Souza-Mello, Vanessa Farias, Jorge
Título	Effectiveness of Copper Nanoparticles in Wound Healing Process Using In Vivo and In Vitro Studies: A Systematic Review
Editorial	MDPI
Revista	PHARMACEUTICS
Lenguaje	en
Resumen	Chronic wounds are defined as wounds that do not heal in an orderly and timely manner through the various stages of the healing process. Copper nanoparticles are essential in dressings for wound healing because they promote angiogenesis and skin regeneration, which hasten the healing process. This systematic investigation sought to explain how copper nanoparticles affect chronic wound healing in vivo and in vitro. We realized a systematic review of original articles studying the effectiveness of copper nanoparticles in the healing process of chronic wounds. The protocol was registered in the PROSPERO database. Several databases were searched between 2012 and January 2022 for English-language papers using MeSH terms and text related to chronic wounds, copper nanoparticles, and wound healing. Quality was evaluated using National Institute for Health and Care Excellence methodology and PRISMA guidelines. We looked at a total of 12 primary studies. Quantitative data were gathered and presented in all studies. Our results suggest that copper nanoparticles could have an excellent healing property, facilitating the liberation of growth factors that help the anti-inflammatory process of the wound and significantly improving antibacterial and antioxidant activities. In addition, copper presents a higher biocompatibility than other metallic ions, promoting regeneration and increasing skin quality.
Tipo de Recurso	artículo de revisión
doi	10.3390/pharmaceutics14091838
Formato Recurso	PDF
Palabras Claves	angiogenesis antimicrobial regeneration nanoparticles MATRIX METALLOPROTEINASES MECHANISMS BACTERIA POLYMER EXPRESSION EFFICACY IMPACT ZINC
Ubicación del archivo	http://dx.doi.org/10.3390/pharmaceutics14091838
Categoría OCDE	Farmacología y farmacia
Materias	angiogénesis antimicrobiano regeneración nanopartículas METALOPROTEINASAS DE MATRIZ MECANISMOS BACTERIAS POLÍMERO EXPRESIÓN EFICACIA IMPACTO ZINC
Disciplinas de la OCDE	Ingeniería Médica Nanomateriales (Producción y Propiedades) Otros Temas de Medicina Básica
Versión del recurso (Recomendado-único)	version publicada
Tipo de ruta	dorada verde
Access Rights	acceso abierto
Derechos de acceso	acceso abierto
Id de Web of Science	WOS:000858929000001
Título de la cita (Recomendado-único)	Effectiveness of Copper Nanoparticles in Wound Healing Process Using In Vivo and In Vitro Studies: A Systematic Review
Identificador del recurso (Mandatado-único)	artículo de revisión
License	CC BY 4.0
Condición de la licencia (Recomendado-repetible)	CC BY 4.0