Repositorio UFRO · Omeka S

Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles

Primer Autor	Calina, Daniela
Co-autores	Sharifi-Rad, Javad Herrera-Bravo, Jesus Semwal, Prabhakar Painuli, Sakshi Badoni, Himani Ezzat, Shahira M. Farid, Mai M. Merghany, Rana M. Aborehab, Nora M. Salem, Mohamed A. Sen, Surjit Acharya, Krishnendu Lapava, Natallia Martorell, Miquel Tynybekov, Bekzat Calina, Daniela Cho, William C.
Título	Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles
Editorial	HINDAWI LTD
Revista	OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
Lenguaje	en
Resumen	Artemisia plants are traditional and ethnopharmacologically used to treat several diseases and in addition in food, spices, and beverages. The genus is widely distributed in all continents except the Antarctica, and traditional medicine has been used as antimalarial, antioxidant, anticancer, antinociceptive, anti-inflammatory, and antiviral agents. This review is aimed at systematizing scientific data on the geographical distribution, chemical composition, and pharmacological and toxicological profiles of the Artemisia genus. Data from the literature on Artemisia plants were taken using electronic databases such as PubMed/MEDLINE, Scopus, and Web of Science. Selected papers for this updated study included data about phytochemicals, preclinical pharmacological experimental studies with molecular mechanisms included, clinical studies, and toxicological and safety data. In addition, ancient texts and books were consulted. The essential oils and phytochemicals of the Artemisia genus have reported important biological activities, among them the artemisinin, a sesquiterpene lactone, with antimalarial activity. Artemisia absinthium L. is one of the most famous Artemisia spp. due to its use in the production of the absinthe drink which is restricted in most countries because of neurotoxicity. The analyzed studies confirmed that Artemisia plants have many traditional and pharmacological applications. However, scientific data are limited to clinical and toxicological research. Therefore, further research is needed on these aspects to understand the full therapeutic potential and molecular pharmacological mechanisms of this medicinal species.
Tipo de Recurso	artículo de revisión
Description	MM wants to thank ANID Centros Basales, ACE210012. MM quiere agradecer a ANID Centros Basales, ACE210012.
doi	10.1155/2022/5628601
Formato Recurso	PDF
Palabras Claves	ESSENTIAL OIL ANTIOXIDANT ACTIVITY MOLECULAR PHYLOGENY ANTICANCER ACTIVITY ALLIES ANTHEMIDEAE FALCIPARUM-MALARIA ENDEMIC ARTEMISIA GENUS ARTEMISIA ABSINTHIUM-L. LEAF EXTRACT
Ubicación del archivo	http://dx.doi.org/10.1155/2022/5628601
Categoría OCDE	Biología Celular
Materias	ACEITE ESENCIAL ACTIVIDAD ANTIOXIDANTE FILOGENIA MOLECULAR ACTIVIDAD ANTICÁNCER ALIADOS ANTHEMIDEAE FALCIPARUM-MALARIA ARTEMISIAENDÉMICA GÉNERO ARTEMISIA ABSINTHIUM-L. EXTRACTO DE HOJA
Disciplinas de la OCDE	Farmacología y Farmacia Toxicología Botánica
Versión del recurso (Recomendado-único)	version publicada
Tipo de ruta	dorada verde
Access Rights	acceso abierto
Derechos de acceso	acceso abierto
Id de Web of Science	WOS:000860025600002
Título de la cita (Recomendado-único)	Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles
Identificador del recurso (Mandatado-único)	artículo de revisión
License	CC BY 4.0
Condición de la licencia (Recomendado-repetible)	CC BY 4.0
Referencia del Financiador (Mandatado si es aplicable-repetible)	ANID ACE210012