Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles
| Primer Autor |
Calina, Daniela
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| Co-autores |
Sharifi-Rad, Javad
Herrera-Bravo, Jesus
Semwal, Prabhakar
Painuli, Sakshi
Badoni, Himani
Ezzat, Shahira M.
Farid, Mai M.
Merghany, Rana M.
Aborehab, Nora M.
Salem, Mohamed A.
Sen, Surjit
Acharya, Krishnendu
Lapava, Natallia
Martorell, Miquel
Tynybekov, Bekzat
Calina, Daniela
Cho, William C.
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| Título |
Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles
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| Editorial |
HINDAWI LTD
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| Revista |
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
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| Lenguaje |
en
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| Resumen |
Artemisia plants are traditional and ethnopharmacologically used to treat several diseases and in addition in food, spices, and beverages. The genus is widely distributed in all continents except the Antarctica, and traditional medicine has been used as antimalarial, antioxidant, anticancer, antinociceptive, anti-inflammatory, and antiviral agents. This review is aimed at systematizing scientific data on the geographical distribution, chemical composition, and pharmacological and toxicological profiles of the Artemisia genus. Data from the literature on Artemisia plants were taken using electronic databases such as PubMed/MEDLINE, Scopus, and Web of Science. Selected papers for this updated study included data about phytochemicals, preclinical pharmacological experimental studies with molecular mechanisms included, clinical studies, and toxicological and safety data. In addition, ancient texts and books were consulted. The essential oils and phytochemicals of the Artemisia genus have reported important biological activities, among them the artemisinin, a sesquiterpene lactone, with antimalarial activity. Artemisia absinthium L. is one of the most famous Artemisia spp. due to its use in the production of the absinthe drink which is restricted in most countries because of neurotoxicity. The analyzed studies confirmed that Artemisia plants have many traditional and pharmacological applications. However, scientific data are limited to clinical and toxicological research. Therefore, further research is needed on these aspects to understand the full therapeutic potential and molecular pharmacological mechanisms of this medicinal species.
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| Tipo de Recurso |
artículo de revisión
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| Description |
MM wants to thank ANID Centros Basales, ACE210012.
MM quiere agradecer a ANID Centros Basales, ACE210012.
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| doi |
10.1155/2022/5628601
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| Formato Recurso |
PDF
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| Palabras Claves |
ESSENTIAL OIL
ANTIOXIDANT ACTIVITY
MOLECULAR PHYLOGENY
ANTICANCER ACTIVITY
ALLIES ANTHEMIDEAE
FALCIPARUM-MALARIA
ENDEMIC ARTEMISIA
GENUS ARTEMISIA
ABSINTHIUM-L.
LEAF EXTRACT
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| Ubicación del archivo | |
| Categoría OCDE |
Biología Celular
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| Materias |
ACEITE ESENCIAL
ACTIVIDAD ANTIOXIDANTE
FILOGENIA MOLECULAR
ACTIVIDAD ANTICÁNCER
ALIADOS ANTHEMIDEAE
FALCIPARUM-MALARIA
ARTEMISIAENDÉMICA
GÉNERO ARTEMISIA
ABSINTHIUM-L.
EXTRACTO DE HOJA
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| Título de la cita (Recomendado-único) |
Artemisia spp.: An Update on Its Chemical Composition, Pharmacological and Toxicological Profiles
|
| Identificador del recurso (Mandatado-único) |
artículo de revisión
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| Versión del recurso (Recomendado-único) |
version publicada
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| License |
CC BY 4.0
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| Condición de la licencia (Recomendado-repetible) |
CC BY 4.0
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| Derechos de acceso |
acceso abierto
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| Access Rights |
acceso abierto
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| Referencia del Financiador (Mandatado si es aplicable-repetible) |
ANID ACE210012
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| Id de Web of Science |
WOS:000860025600002
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cienciaabierta.ufro.cl
ciencia.abierta@ufrontera.cl