Repositorio UFRO · Omeka S

Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements

Primer Autor	Santos, Andres
Co-autores	Burgos, Felipe Martinez-Urtaza, Jaime Barrientos, Leticia
Título	Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements
Editorial	MDPI
Revista	MICROORGANISMS
Lenguaje	en
Resumen	Antibiotic resistance genes (ARGs) are undergoing a remarkably rapid geographic expansion in various ecosystems, including pristine environments such as Antarctica. The study of ARGs and environmental resistance genes (ERGs) mechanisms could provide a better understanding of their origin, evolution, and dissemination in these pristine environments. Here, we describe the diversity of ARGs and ERGs and the importance of mobile genetic elements as a possible mechanism for the dissemination of resistance genes in Antarctica. We analyzed five soil metagenomes from Deception Island in Antarctica. Results showed that detected ARGs are associated with mechanisms such as antibiotic efflux, antibiotic inactivation, and target alteration. On the other hand, resistance to metals, surfactants, and aromatic hydrocarbons were the dominant ERGs. The taxonomy of ARGs showed that Pseudomonas, Psychrobacter, and Staphylococcus could be key taxa for studying antibiotic resistance and environmental resistance to stress in Deception Island. In addition, results showed that ARGs are mainly associated with phage-type mobile elements suggesting a potential role in their dissemination and prevalence. Finally, these results provide valuable information regarding the ARGs and ERGs in Deception Island including the potential contribution of mobile genetic elements to the spread of ARGs and ERGs in one of the least studied Antarctic ecosystems to date.
Tipo de Recurso	artículo original
Description	This research was funded by Fondecyt Regular Nffi 1210563, grants DI19-0079, and grant CONICYT-Doctorado Nacional-2017-21171392 for A.S. Esta investigación fue financiada por Fondecyt Regular Nffi 1210563, becas DI19-0079, y beca CONICYT-Doctorado Nacional-2017-21171392 para A.S. This research was funded by Fondecyt Regular Nffi 1210563; grants DI19-0079, and grant CONICYT-Doctorado Nacional-2017-21171392 for A.S. Esta investigación fue financiada por Fondecyt Regular Nffi 1210563; becas DI19-0079, y beca CONICYT-Doctorado Nacional-2017-21171392 para A.S.
doi	10.3390/microorganisms10071432
Formato Recurso	PDF
Palabras Claves	Antarctic soils phages plasmids pristine environments SOUTH SHETLAND ISLANDS ANTIBIOTIC-RESISTANCE METAL RESISTANCE ENVIRONMENTS BACTERIA ARGS
Ubicación del archivo	http://dx.doi.org/10.3390/microorganisms10071432
Categoría OCDE	Microbiología
Materias	Suelos antárticos fagos plásmidos ambientes prístinos ISLAS SHETLAND DEL SUR RESISTENCIA A LOS ANTIBIÓTICOS RESISTENCIA A LOS METALES AMBIENTE BACTERIAS ARGS
Disciplinas de la OCDE	Microbiología Biología Molecular Ecología
Título de la cita (Recomendado-único)	Metagenomic Characterization of Resistance Genes in Deception Island and Their Association with Mobile Genetic Elements
Identificador del recurso (Mandatado-único)	artículo original
Versión del recurso (Recomendado-único)	version publicada
License	CC BY 4.0
Condición de la licencia (Recomendado-repetible)	CC BY 4.0
Derechos de acceso	acceso abierto
Access Rights	acceso abierto
Referencia del Financiador (Mandatado si es aplicable-repetible)	ANID-FONDECYT 1210563 UFRO DI19-0079 ANID 21171392 ANID FONDECYT 1210563
Id de Web of Science	WOS:000833847500001