Biomarkers in Oral Fluids as Diagnostic Tool for Psoriasis

Primer Autor
Fernandez, Alejandra
Co-autores
Jimenez, Constanza
Jose Bordagaray, Maria
Luis Villarroel, Jose
Flores, Tania
Benadof, Dafna
Valenzuela, Fernando
Título
Biomarkers in Oral Fluids as Diagnostic Tool for Psoriasis
Editorial
MDPI
Revista
LIFE-BASEL
Lenguaje
en
Resumen
"Psoriasis is a prevalent worldwide chronic immuno-inflammatory skin disease with various variants and atypical cases. The use of biomarkers for the diagnosis of psoriasis can favor timely treatment and thus improve the quality of life of those affected. In general, the search for biomarkers in oral fluids is recommended as it is a non-invasive and fast technique. This narrative review aimed to identify biomarkers in gingival crevicular fluid (GCF) and saliva to diagnose psoriasis. To achieve this goal, we selected the available literature using the following MESH terms: ""psoriasis"", ""saliva"" and ""gingival crevicular fluid"". The studies analyzed for this review cover original research articles available in English. We found three full articles available for psoriasis biomarkers in GCF and ten articles available for psoriasis biomarkers in saliva. Studies showed that in the saliva of healthy individuals and those with psoriasis, there were differences in the levels of inflammatory cytokines, immunoglobulin A, and antioxidant biomarkers. In GCF, individuals with psoriasis showed higher levels of S100A8, IL-18 and sE-selectin in comparison to healthy individuals, independent of periodontal status. Despite these findings, more studies are required to determine an adequate panel of biomarkers to use in saliva or GCF for psoriasis."
Tipo de Recurso
artículo de revisión
doi
10.3390/life12040501
Formato Recurso
PDF
Palabras Claves
psoriasis
biomarkers
saliva
gingival crevicular fluid
GINGIVAL CREVICULAR FLUID
NECROSIS-FACTOR-ALPHA
T-CELLS
PERIODONTAL-DISEASES
FUTURE-DIRECTIONS
PAROTID-SALIVA
CYTOKINES
PLAQUE
IMMUNOGLOBULINS
COLLECTION
Ubicación del archivo
http://dx.doi.org/10.3390/life12040501
Categoría OCDE
Biología
Microbiología
Materias
psoriasis
biomarcadores
saliva
líquido crevicular gingival
FLUIDO CREVICULAR GINGIVAL
NECROSIS-FACTOR-ALFA
CÉLULAS-T
ENFERMEDADES-PERIODONTALES
DIRECCIONES-FUTURAS
SALIVA-PARÓTIDA
CITOQUINAS
PLACA
INMUNOGLOBULINAS
COLECCIÓN
Título de la cita (Recomendado-único)
Biomarkers in Oral Fluids as Diagnostic Tool for Psoriasis
Identificador del recurso (Mandatado-único)
artículo de revisión
Versión del recurso (Recomendado-único)
version publicada
License
CC BY 4.0
Condición de la licencia (Recomendado-repetible)
CC BY 4.0
Derechos de acceso
acceso abierto
Access Rights
acceso abierto
Id de Web of Science
WOS:000785401900001
Colecciones
Colección Publicaciones Científicas
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