Repositorio UFRO · Omeka S

Biomarkers in Oral Fluids as Diagnostic Tool for Psoriasis

Primer Autor	Fernandez, Alejandra
Co-autores	Jimenez, Constanza Jose Bordagaray, Maria Luis Villarroel, Jose Flores, Tania Benadof, Dafna Valenzuela, Fernando
Título	Biomarkers in Oral Fluids as Diagnostic Tool for Psoriasis
Editorial	MDPI
Revista	LIFE-BASEL
Lenguaje	en
Resumen	"Psoriasis is a prevalent worldwide chronic immuno-inflammatory skin disease with various variants and atypical cases. The use of biomarkers for the diagnosis of psoriasis can favor timely treatment and thus improve the quality of life of those affected. In general, the search for biomarkers in oral fluids is recommended as it is a non-invasive and fast technique. This narrative review aimed to identify biomarkers in gingival crevicular fluid (GCF) and saliva to diagnose psoriasis. To achieve this goal, we selected the available literature using the following MESH terms: ""psoriasis"", ""saliva"" and ""gingival crevicular fluid"". The studies analyzed for this review cover original research articles available in English. We found three full articles available for psoriasis biomarkers in GCF and ten articles available for psoriasis biomarkers in saliva. Studies showed that in the saliva of healthy individuals and those with psoriasis, there were differences in the levels of inflammatory cytokines, immunoglobulin A, and antioxidant biomarkers. In GCF, individuals with psoriasis showed higher levels of S100A8, IL-18 and sE-selectin in comparison to healthy individuals, independent of periodontal status. Despite these findings, more studies are required to determine an adequate panel of biomarkers to use in saliva or GCF for psoriasis."
Tipo de Recurso	artículo de revisión
doi	10.3390/life12040501
Formato Recurso	PDF
Palabras Claves	psoriasis biomarkers saliva gingival crevicular fluid GINGIVAL CREVICULAR FLUID NECROSIS-FACTOR-ALPHA T-CELLS PERIODONTAL-DISEASES FUTURE-DIRECTIONS PAROTID-SALIVA CYTOKINES PLAQUE IMMUNOGLOBULINS COLLECTION
Ubicación del archivo	http://dx.doi.org/10.3390/life12040501
Categoría OCDE	Biología Microbiología
Materias	psoriasis biomarcadores saliva líquido crevicular gingival FLUIDO CREVICULAR GINGIVAL NECROSIS-FACTOR-ALFA CÉLULAS-T ENFERMEDADES-PERIODONTALES DIRECCIONES-FUTURAS SALIVA-PARÓTIDA CITOQUINAS PLACA INMUNOGLOBULINAS COLECCIÓN
Disciplinas de la OCDE	Dermatología y Enfermedades Venéreas Biología Molecular Odontología, Cirugía y Medicina Oral
Versión del recurso (Recomendado-único)	version publicada
Tipo de ruta	dorada verde
Access Rights	acceso abierto
Derechos de acceso	acceso abierto
Id de Web of Science	WOS:000785401900001
Título de la cita (Recomendado-único)	Biomarkers in Oral Fluids as Diagnostic Tool for Psoriasis
Identificador del recurso (Mandatado-único)	artículo de revisión
License	CC BY 4.0
Condición de la licencia (Recomendado-repetible)	CC BY 4.0