A cross sectional study found differential risks for COVID-19 seropositivity amongst health care professionals in Chile

Primer Autor
O'Ryan, Miguel L.
Co-autores
Zuniga, Marcela
Lagomarcino, Anne J.
Munoz, Sergio
Pena Alonso, Alfredo
Andrea Rodriguez, Maria
Título
A cross sectional study found differential risks for COVID-19 seropositivity amongst health care professionals in Chile
Editorial
ELSEVIER SCIENCE INC
Revista
JOURNAL OF CLINICAL EPIDEMIOLOGY
Lenguaje
en
Resumen
Objective: Health care workers (HCWs) are at increased risk for SARS-CoV-2 infection, however not all face the same risk. We aimed to determine IgG/IgM prevalence and risk factors associated with seropositivity in Chilean HCWs. Study Design and Setting: This was a nationwide, cross-sectional study including a questionnaire and COVID-19 lateral flow IgG/IgM antibody testing. All HCWs in the Chilean public health care system were invited to participate following the country's first wave. Results: IgG/IgM positivity in 85,529 HCWs was 7.2%, ranging from 1.6% to 12.4% between regions. Additionally, 9.7% HCWs reported a positive PCR of which 47% were seropositive. Overall, 10,863 (12.7%) HCWs were PCR and/or IgG/IgM positive. Factors independently associated with increased odds ratios (ORs) for seropositivity were: working in a hospital, night shifts, contact with Covid-19, using public transport, male gender, age >45, BMI >= 30, and reporting >= 2 symptoms. Stress and/or mental health disorder and smoking were associated with decreased ORs. These factors remained significant when including PCR positive cases in the model. Conclusions: HCWs in the hospital were at highest risk for COVID-19, and several independent risk factors for seropositivity and/or PCR positivity were identified. (C) 2021 Elsevier Inc. All rights reserved.
Tipo de Recurso
artículo original
doi
10.1016/j.jclinepi.2021.12.026
Formato Recurso
PDF
Palabras Claves
Health care workers
COVID-19
Antibody prevalence
Vaccine priority
SARS-CoV-2
Antibody testing
SARS-COV-2
SEROPREVALENCE
Ubicación del archivo
http://dx.doi.org/10.1016/j.jclinepi.2021.12.026
Categoría OCDE
Ciencias y Servicios de Atención Médica
Salud pública
ambiental y ocupacional
Materias
Trabajadores de la salud
COVID-19
Prevalencia de anticuerpos
Prioridad de la vacuna
SARS-CoV-2
Pruebas de anticuerpos
SARS-COV-2
SEROPREVALENCIA
Título de la cita (Recomendado-único)
A cross sectional study found differential risks for COVID-19 seropositivity amongst health care professionals in Chile
Página de inicio (Recomendado-único)
72
Página final (Recomendado-único)
83
Identificador del recurso (Mandatado-único)
artículo original
Versión del recurso (Recomendado-único)
version publicada
Condición de la licencia (Recomendado-repetible)
0
Derechos de acceso
acceso abierto
Access Rights
acceso abierto
Id de Web of Science
WOS:000786657100005
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Colección Publicaciones Científicas
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