Salivary Microbial Dysbiosis Is Associated With Peri-Implantitis: A Case-Control Study in a Brazilian Population
| Primer Autor |
Braz-Silva, Paulo Henrique
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| Co-autores |
Pallos, Debora
Sousa, Vanessa
Feres, Magda
Retamal-Valdes, Belen
Chen, Tsute
Curtis, Mike
Boaventura, Richardson Mondego
Tanaka, Marcia Hiromi
Salomao, Gustavo Vargas da Silva
Zanella, Louise
Tozetto-Mendoza, Tania Regina
Schwab, Gabriela
Franco, Lucas Augusto Moyses
Sabino, Ester Cerdeira
Shibli, Jamil Awad
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| Título |
Salivary Microbial Dysbiosis Is Associated With Peri-Implantitis: A Case-Control Study in a Brazilian Population
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| Editorial |
FRONTIERS MEDIA SA
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| Revista |
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
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| Lenguaje |
en
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| Resumen |
Background and ObjectivesThe aim of this study was to examine the salivary microbiome in healthy peri-implant sites and those with peri-implantitis. MethodsSaliva samples were collected from 21 participants with healthy peri-implant sites and 21 participants with peri-implantitis. The V4 hypervariable region of the 16S rRNA gene was sequenced using the Ion Torrent PGM System (Ion 318 (TM) Chip v2 400). The NGS analysis and composition of the salivary microbiome were determined by taxonomy assignment. Downstream bioinformatic analyses were performed in QIIME (v 1.9.1). ResultsClinical differences according to peri-implant condition status were found. Alpha diversity metrics revealed that the bacterial communities of participants with healthy peri-implant sites tended to have a richer microbial composition than individuals with peri-implantitis. In terms of beta diversity, bleeding on probing (BoP) may influence the microbial diversity. However, no clear partitioning was noted between the salivary microbiome of volunteers with healthy peri-implant sites or volunteers with peri-implantitis. The highest relative abundance of Stenotrophomonas, Enterococcus and Leuconostoc genus, and Faecalibacterium prausnitzii, Haemophilus parainfluenzae, Prevotella copri, Bacteroides vulgatus, and Bacteroides stercoris bacterial species was found in participants with peri-implantitis when compared with those with healthy peri-implant sites. ConclusionDifferences in salivary microbiome composition were observed between patients with healthy peri-implant sites and those with peri-implantitis. BoP could affect the diversity (beta diversity) of the salivary microbiome.
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| Tipo de Recurso |
artículo original
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| Description |
This study was supported by grants from the Sao Paulo Research Foundation (FAPESP)-grant numbers: 2013/08242-3 and 2015/07727-9, Brazilian Coordination for the Improvement of Higher Education Personnel (CAPES)-financial code 001, National Council for Scientific and Technological Development (CNPq)-grant numbers: 311368/2019-0 and 44004/2014-5, National Institute of Health Research (NIHR CL), National Funding for Scientific and Technologic Development of Chile (FONDECYT)-grant number: 3210687, Universidad de La Frontera (DIUFRO)-grant number: DIM20-0019, and Universidad de La Frontera-grant number: VRIP20P002.
Este estudio fue apoyado por subvenciones de la Fundación de Investigación de São Paulo (FAPESP): números de subvención: 2013/08242-3 y 2015/07727-9, Coordinación Brasileña de Perfeccionamiento del Personal de Educación Superior (CAPES) - código financiero 001, Consejo Nacional de Desarrollo Científico y Tecnológico (CNPq) - números de concesión: 311368/2019-0 y 44004/2014-5, Instituto Nacional de Investigaciones en Salud (NIHR CL), Fondo Nacional para el Desarrollo Científico y Tecnológico de Chile (FONDECYT) -número de concesión: 3210687, Universidad de La Frontera (DIUFRO)-número de subvención: DIM20-0019, y Universidad de La Frontera-número de subvención: VRIP20P002.
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| doi |
10.3389/fcimb.2021.696432
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| Formato Recurso |
PDF
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| Palabras Claves |
peri-implantitis
saliva
microbiota (16S)
host-bacteria interaction
dysbioses
BIOFILM
HEALTHY
SUPRAGINGIVAL
DIVERSITY
SITES
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| Ubicación del archivo | |
| Categoría OCDE |
Inmunología
Microbiología
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| Materias |
periimplantitis
saliva
microbiota (16S)
interacción huésped-bacteria
disbiosis
BIOFILM
SALUD
SUPRAGINGIVAL
DIVERSIDAD
SITIOS
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| Título de la cita (Recomendado-único) |
Salivary Microbial Dysbiosis Is Associated With Peri-Implantitis: A Case-Control Study in a Brazilian Population
|
| Identificador del recurso (Mandatado-único) |
artículo original
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| Versión del recurso (Recomendado-único) |
version publicada
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| License |
CC BY 4.0
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| Condición de la licencia (Recomendado-repetible) |
CC BY 4.0
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| Derechos de acceso |
acceso abierto
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| Access Rights |
acceso abierto
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| Referencia del Financiador (Mandatado si es aplicable-repetible) |
FAPESP 2013/08242-3
FAPESP 2015/07727-9
CNPQ 311368/2019-0
CNPQ 44004/2014-5
ANID-FONDECYT 3210687
UFRO DIM20-0019
UFRO VRIP20P002
ANID FONDECYT 3210687
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| Id de Web of Science |
WOS:000745786400001
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cienciaabierta.ufro.cl
ciencia.abierta@ufrontera.cl