Repositorio
Institucional

Calina, Daniela

Konovalov, Dmitryi Alexeevich

Caceres, Edgardo Avendano

Shcherbakova, Ekaterina Aleksandrovna

Herrera-Bravo, Jesus

Chandran, Deepak

Martorell, Miquel

Hasan, Muzaffar

Kumar, Manoj

Bakrim, Saad

Bouyahya, Abdelhakim

Cho, William C.

Sharifi-Rad, Javad

Suleria, Hafiz A. R.

Eryngium caeruleum: an update on ethnobotany, phytochemistry and biomedical applications

BMC

CHINESE MEDICINE

en

Background A biennial or perennial plant of the Apiaceae family, Eryngium caeruleum M. Bieb. is traditionally used in medicine as an antitoxic, diuretic, digestive, anti-inflammatory and analgesic drug. This plant is widely distributed in temperate regions around the world. Young leaves of the plant are used in cooking as aromatic cooked vegetables in various local products in Iran. Purpose The current review aimed to highlight complete and updated information about the Eryngium caeruleum species, regarding botanical, ethnopharmacological, phytochemical data, pharmacological mechanisms as well as some nutritional properties. All this scientific evidence supports the use of this species in complementary medicine, thus opening new therapeutic perspectives for the treatment of some diseases. Methods The information provided in this updated review is collected from several scientific databases such as PubMed/Medline, ScienceDirect, Mendeley, Scopus, Web of Science and Google Scholar. Ethnopharmacology books and various professional websites were also researched. Results The phytochemical composition of the aerial parts and roots of E. caeruleum is represented by the components of essential oil (EO), phenolic compounds, saponins, protein, amino acids, fiber, carbohydrates, and mineral elements. The antioxidant, antimicrobial, antidiabetic, antihypoxic, and anti-inflammatory properties of E. caeruleum have been confirmed by pharmacological experiments with extracts using in vitro and in vivo methods. The syrup E. caeruleum relieved dysmenorrhea as effectively as Ibuprofen in the blinded, randomized, placebo-controlled clinical study. Conclusion Current evidence from experimental pharmacological studies has shown that the different bioactive compounds present in the species E. caeruleum have multiple beneficial effects on human health, being potentially active in the treatment of many diseases. Thus, the traditional uses of this species are supported based on evidence. In future, translational and human clinical studies are necessary to establish effective therapeutic doses in humans.

artículo de revisión

Authors acknowledge Pyatigorsk Medical-Pharmaceutical Institute (PMPI), Branch of Volgograd State Medical University, Ministry of Health of Russia, Pyatigorsk, Russian Federation. MM wants to thank ANID CENTROS BASALES ACE210012.

Los autores agradecen al Instituto Médico-Farmacéutico de Pyatigorsk (PMPI), sucursal de la Universidad Médica Estatal de Volgogrado, Ministerio de Salud de Rusia, Pyatigorsk, Federación de Rusia. MM quiere agradecer a ANID CENTROS BASALES ACE210012.

10.1186/s13020-022-00672-x

PDF

Eryngium caeruleum

Ethnobotany

Bioactive molecules

Pharmacological activities

BIOLOGICAL-ACTIVITIES

ANTIOXIDANT ACTIVITY

CAUCASICUM TRAUTV.

ESSENTIAL OILS

APIACEAE

PLANTS

SANICULOIDEAE

CONSTITUENTS

RIBAVIRIN

THERAPY

Medicina Integrativa y Complementaria

Farmacología y farmacia

Eryngium caeruleum

Etnobotánica

Moléculas bioactivas

Actividades farmacológicas

ACTIVIDADES BIOLÓGICAS

ACTIVIDAD ANTIOXIDANTE

CAUCASICUM TRAUTV.

ACEITES ESENCIALES

APIACEAE

PLANTAS

SANICULOIDEAE

CONSTITUENTES

RIBAVIRINA

TERAPIA

Farmacología y Farmacia

Medicina Integrativa y Complementaria (Sistemas de Práctica Alternativa)

Botánica

Eryngium caeruleum: an update on ethnobotany, phytochemistry and biomedical applications

artículo de revisión

version publicada

CC BY 4.0

CC BY 4.0

acceso abierto

acceso abierto

ANID ACE210012

WOS:000861917400001