Repositorio UFRO · Omeka S

Myricetin: targeting signaling networks in cancer and its implication in chemotherapy

Primer Autor	Iqbal, Muhammad Javed
Co-autores	Javed, Zeeshan Khan, Khushbukhat Herrera-Bravo, Jesus Naeem, Sajid Raza, Qamar Sadia, Haleema Raza, Shahid Bhinder, Munir Calina, Daniela Sharifi-Rad, Javad Cho, William C.
Título	Myricetin: targeting signaling networks in cancer and its implication in chemotherapy
Editorial	BMC
Revista	CANCER CELL INTERNATIONAL
Lenguaje	en
Resumen	The gaps between the complex nature of cancer and therapeutics have been narrowed down due to extensive research in molecular oncology. Despite gathering massive insight into the mysteries of tumor heterogeneity and the molecular framework of tumor cells, therapy resistance and adverse side effects of current therapeutic remain the major challenge. This has shifted the attention towards therapeutics with less toxicity and high efficacy. Myricetin a natural flavonoid has been under the spotlight for its anti-cancer, anti-oxidant, and anti-inflammatory properties. The cutting-edge molecular techniques have shed light on the interplay between myricetin and dysregulated signaling cascades in cancer progression, invasion, and metastasis. However, there are limited data available regarding the nano-delivery platforms composed of myricetin in cancer. In this review, we have provided a comprehensive detail of myricetin-mediated regulation of different cellular pathways, its implications in cancer prevention, preclinical and clinical trials, and its current available nano-formulations for the treatment of various cancers.
Tipo de Recurso	artículo de revisión
doi	10.1186/s12935-022-02663-2
Formato Recurso	PDF
Palabras Claves	Myricetin Cancer Signaling networks Apoptosis Cell cycle Nano-delivery DIETARY FLAVONOID INTAKE IN-VITRO CELL-DEATH INHIBITS PROLIFERATION PROSTATE-CANCER LUNG-CANCER HEPG2 CELLS APOPTOSIS EXPRESSION PATHWAY
Ubicación del archivo	http://dx.doi.org/10.1186/s12935-022-02663-2
Categoría OCDE	Oncología
Materias	Miricetina Cáncer Redes de señalización Apoptosis Ciclo celular Nanoentrega INGESTA DE FLAVONOIDES DIETÉTICOS IN VITRO MUERTE CELULAR INHIBE LA PROLIFERACIÓN CÁNCER DE PRÓSTATA CÁNCER DE PULMÓN CÉLULAS HEPG2 APOPTOSIS EXPRESIÓN CAMINO
Disciplinas de la OCDE	Oncología Biología Molecular Farmacología y Farmacia
Título de la cita (Recomendado-único)	Myricetin: targeting signaling networks in cancer and its implication in chemotherapy
Identificador del recurso (Mandatado-único)	artículo de revisión
Versión del recurso (Recomendado-único)	version publicada
License	CC BY 4.0
Condición de la licencia (Recomendado-repetible)	CC BY 4.0
Derechos de acceso	acceso abierto
Access Rights	acceso abierto
Id de Web of Science	WOS:000832677200002