Repositorio
Institucional

Meza, Nicolas

Bracchiglione, Javier

Franco, Juan Victor Ariel

Escobar Liquitay, Camila Micaela

Munoz, Sergio R.

Urrutia, Gerard

Madrid, Eva

Mapping Chilean clinical research: a protocol for a scoping review and multiple evidence gap maps

BMJ PUBLISHING GROUP

BMJ OPEN

en

Introduction Clinical research broadly aims to influence decision-making in order to promote appropriate healthcare. Funding agencies should prioritise research projects according to needed research topics, methodological and cost-effectiveness considerations, and expected social value. In Chile, there is no local diagnosis regarding recent clinical research that might inform prioritisation for future research funding. This research aims to comprehensively identify and classify Chilean health research studies, elaborating evidence gap maps for the most burdensome local conditions. Methods and analysis We will search in electronic databases (MEDLINE, Embase, PsycINFO, CINAHL, LILACS and WoS) and perform hand searches to retrieve, identify and classify health research studies conducted in Chile or by authors whose affiliations are based in Chile, from 2000 onwards. We will elaborate evidence matrices for the 20 conditions with the highest burden in Chile (according to the Global Burden of Disease 2019) selected from those defined under the General Regime of the Health Guarantees Act. To elaborate the evidence gap maps, we will consider prioritised interventions and core outcome sets. To identify knowledge gaps and estimate redundant research, we will contrast these gap maps with the available international evidence of high or moderate certainty of evidence, for each specific clinical question. For this purpose, we will search systematic reviews using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. Ethics and dissemination No ethical approval is required to conduct this project. We will submit our results in both peer-reviewed journals and scientific conferences. We will aim to disseminate our findings through different academic platforms, social media, local press, among others. The final results will be communicated to local funding agencies and government stakeholders. Discussion We aim to provide an accurate and up-to-date picture of the research gaps-to be filled by new future findings-and the identification of redundant research, which will constitute relevant information for local decision-makers.

artículo de revisión

FONDECYT Grant 1212037 from the Chilean National Agency of Research and Development (ANID).

Beca FONDECYT 1212037 de la Agencia Nacional de Investigación y Desarrollo (ANID) de Chile.

10.1136/bmjopen-2021-057555

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PUBLIC HEALTH

STATISTICS & RESEARCH METHODS

HEALTH SERVICES ADMINISTRATION & MANAGEMENT

REDUCING WASTE

RESEARCH PRIORITIES

INCREASING VALUE

PUBLIC-HEALTH

REFORM

RISK

BIAS

TOOL

Medicina general e interna

SALUD PÚBLICA

ESTADÍSTICAS Y MÉTODOS DE INVESTIGACIÓN

ADMINISTRACIÓN Y GESTIÓN DE SERVICIOS DE SALUD

REDUCCIÓN DE RESIDUOS

PRIORIDADES DE INVESTIGACIÓN

AUMENTAR EL VALOR

REFORMA

RIESGO

SESGO

HERRAMIENTA

Mapping Chilean clinical research: a protocol for a scoping review and multiple evidence gap maps

artículo de revisión

version publicada

CC BY 4.0

CC BY 4.0

acceso abierto

acceso abierto

ANID-FONDECYT 1212037

ANID FONDECYT 1212037

WOS:000814420600033