Therapeutic Applications of Curcumin in Diabetes: A Review and Perspective

Primer Autor
Martorell, Miquel
Co-autores
Quispe, Cristina
Herrera-Bravo, Jesus
Javed, Zeeshan
Khan, Khushbukhat
Raza, Shahid
Gulsunoglu-Konuskan, Zehra
Dastan, Sevgi Durna
Sytar, Oksana
Sharifi-Rad, Javad
Calina, Daniela
Título
Therapeutic Applications of Curcumin in Diabetes: A Review and Perspective
Editorial
HINDAWI LTD
Revista
BIOMED RESEARCH INTERNATIONAL
Lenguaje
en
Resumen
Diabetes is a metabolic disease with multifactorial causes which requires lifelong drug therapy as well as lifestyle changes. There is now growing scientific evidence to support the effectiveness of the use of herbal supplements in the prevention and control of diabetes. Curcumin is one of the most studied bioactive components of traditional medicine, but its physicochemical characteristics are represented by low solubility, poor absorption, and low efficacy. Nanotechnology-based pharmaceutical formulations can help overcome the problems of reduced bioavailability of curcumin and increase its antidiabetic effects. The objectives of this review were to review the effects of nanocurcumin on DM and to search for databases such as PubMed/MEDLINE and ScienceDirect. The results showed that the antidiabetic activity of nanocurcumin is due to complex pharmacological mechanisms by reducing the characteristic hyperglycemia of DM. In light of these results, nanocurcumin may be considered as potential agent in the pharmacotherapeutic management of patients with diabetes.
Tipo de Recurso
artículo de revisión
doi
10.1155/2022/1375892
Formato Recurso
PDF
Palabras Claves
DRUG-DELIVERY
CHITOSAN NANOPARTICLES
OXIDE NANOPARTICLES
LIPID PROFILE
NANO-CURCUMIN
FORMULATION
OPTIMIZATION
EXTRACTION
STRESS
NANOCRYSTALS
Ubicación del archivo
http://dx.doi.org/10.1155/2022/1375892
Categoría OCDE
Biotecnología y Microbiología Aplicada
Medicina
Investigación y Experimental
Materias
ENTREGA DE MEDICAMENTOS
NANOPARTÍCULAS DE QUITOSANO
NANOPARTÍCULAS DE ÓXIDO
PERFIL LIPÍDICO
NANOCURCUMINA
FORMULACIÓN
OPTIMIZACIÓN
EXTRACCIÓN
ESTRÉS
NANOCRISTALES
Disciplinas de la OCDE
Endocrinología y Metabolismo (Incluye Diabetes, Hormonas)
Farmacología y Farmacia
Nanomateriales (Producción y Propiedades)
Título de la cita (Recomendado-único)
Therapeutic Applications of Curcumin in Diabetes: A Review and Perspective
Identificador del recurso (Mandatado-único)
artículo de revisión
Versión del recurso (Recomendado-único)
version publicada
License
CC BY 4.0
Condición de la licencia (Recomendado-repetible)
CC BY 4.0
Derechos de acceso
acceso abierto
Access Rights
acceso abierto
Id de Web of Science
WOS:000777273400002
Colecciones
Colección Publicaciones Científicas
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