Vitamin Supplements as a Nutritional Strategy against Chronic Alcohol Consumption? An Updated Review

Primer Autor
Sandoval, Cristian
Co-autores
Farias, Jorge
Zamorano, Mauricio
Herrera, Christian
Título
Vitamin Supplements as a Nutritional Strategy against Chronic Alcohol Consumption? An Updated Review
Editorial
MDPI
Revista
ANTIOXIDANTS
Lenguaje
en
Resumen
Several studies have shown that blood vitamin levels are low in alcoholic patients. In effect, alcohol use abuse is considered a chronic disease that promotes the pathogenesis of many fatal diseases, such as cancer and liver cirrhosis. The alcohol effects in the liver can be prevented by antioxidant mechanisms, which induces enzymatic as well as other nonenzymatic pathways. The effectiveness of several antioxidants has been evaluated. However, these studies have been accompanied by uncertainty as mixed results were reported. Thus, the aim of the present review article was to examine the current knowledge on vitamin deficiency and its role in chronic liver disease. Our review found that deficiencies in nutritional vitamins could develop rapidly during chronic liver disease due to diminished hepatic storage and that inadequate vitamins intake and alcohol consumption may interact to deplete vitamin levels. Numerous studies have described that vitamin supplementation could reduce hepatotoxicity. However, further studies with reference to the changes in vitamin status and the nutritional management of chronic liver disease are in demand.
Tipo de Recurso
artículo original
doi
10.3390/antiox11030564
Formato Recurso
PDF
Palabras Claves
alcoholic liver disease
vitamin B1
vitamin C
vitamin D
vitamin E
ASCORBIC-ACID SUPPLEMENTATION
PLACEBO-CONTROLLED TRIAL
INDUCED OXIDATIVE STRESS
WATER-SOLUBLE VITAMINS
SEMI-PURIFIED DIET
LIPID-PEROXIDATION
LIVER-DISEASE
D DEFICIENCY
S-ADENOSYLMETHIONINE
ETHANOL-METABOLISM
Ubicación del archivo
http://dx.doi.org/10.3390/antiox11030564
Categoría OCDE
Bioquímica y Biología Molecular
Química Medicinal
Ciencia y tecnología de los alimentos
Materias
enfermedad hepática alcohólica
vitamina B1
vitamina C
vitamina D
vitamina E
SUPLEMENTACIÓN DE ÁCIDO ASCÓRBICO
ensayo controlado con placebo
ESTRÉS OXIDATIVO INDUCIDO
VITAMINAS SOLUBLES EN AGUA
DIETA SEMIPURIFICADA
PEROXIDACIÓN LÍPIDA
ENFERMEDAD DEL HÍGADO
DEFICIENCIA D
S-ADENOSILMETIONINA
ETANOL-METABOLISMO
Disciplinas de la OCDE
Gastroenterología y Hepatología
Nutrición y Dietética
Medicina General e Interna
Título de la cita (Recomendado-único)
Vitamin Supplements as a Nutritional Strategy against Chronic Alcohol Consumption? An Updated Review
Identificador del recurso (Mandatado-único)
artículo original
Versión del recurso (Recomendado-único)
version publicada
License
CC BY 4.0
Condición de la licencia (Recomendado-repetible)
CC BY 4.0
Derechos de acceso
acceso abierto
Access Rights
acceso abierto
Id de Web of Science
WOS:000776907700001
Colecciones
Colección Publicaciones Científicas
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