Repositorio UFRO · Omeka S

Pluripotent Core in Bovine Embryos: A Review

Primer Autor	Aguila, Luis
Co-autores	Osycka-Salut, Claudia Treulen, Favian Felmer, Ricardo
Título	Pluripotent Core in Bovine Embryos: A Review
Editorial	MDPI
Revista	ANIMALS
Lenguaje	en
Resumen	Simple Summary The fusion between sperm and oocyte results in a zygote, which is a single totipotent cell with the ability to develop into a functional organism. Totipotent cells can give rise to different specialized cell types of all lineages. Understanding the interactions between cell signaling pathways, which drive the early embryo to maintain pluripotency, is essential to establishing the optimal embryonic or stem cell culture conditions for biotechnological applications in cattle. Thus, this review summarizes the core of pluripotency genes, strategies for controlling pluripotency, and the potential applications of pluripotency in in vitro production of cattle embryos. Early development in mammals is characterized by the ability of each cell to produce a complete organism plus the extraembryonic, or placental, cells, defined as pluripotency. During subsequent development, pluripotency is lost, and cells begin to differentiate to a particular cell fate. This review summarizes the current knowledge of pluripotency features of bovine embryos cultured in vitro, focusing on the core of pluripotency genes (OCT4, NANOG, SOX2, and CDX2), and main chemical strategies for controlling pluripotent networks during early development. Finally, we discuss the applicability of manipulating pluripotency during the morula to blastocyst transition in cattle species.
Tipo de Recurso	artículo de revisión
doi	10.3390/ani12081010
Formato Recurso	PDF
Palabras Claves	cattle in vitro technologies stem cells IVF LEUKEMIA INHIBITORY FACTOR EARLY LINEAGE SEGREGATION INNER CELL MASS IN-VITRO PREIMPLANTATION DEVELOPMENT GENE-EXPRESSION TROPHECTODERM LINEAGE PRIMITIVE ENDODERM NUCLEAR TRANSFER STEM-CELLS
Ubicación del archivo	http://dx.doi.org/10.3390/ani12081010
Categoría OCDE	Agricultura Lácteos y Ciencia Animal Ciencias Veterinarias Zoología
Materias	ganado tecnologías in vitro células madre FIV FACTOR INHIBIDOR DE LA LEUCEMIA SEGREGACIÓN DEL LINAJE TEMPRANO MASA CELULAR INTERNA IN VITRO DESARROLLO PREIMPLANTACIÓN EXPRESIÓN GENÉTICA LINAJE DEL TROFECTODERMO ENDODERMO PRIMITIVO TRANSFERENCIA NUCLEAR CÉLULAS MADRE
Disciplinas de la OCDE	Biología Molecular Biología del Desarrollo Ciencias Veterinarias
Versión del recurso (Recomendado-único)	version publicada
Tipo de ruta	dorada verde
Access Rights	acceso abierto
Derechos de acceso	acceso abierto
Id de Web of Science	WOS:000785463500001
Título de la cita (Recomendado-único)	Pluripotent Core in Bovine Embryos: A Review
Identificador del recurso (Mandatado-único)	artículo de revisión
License	CC BY 4.0
Condición de la licencia (Recomendado-repetible)	CC BY 4.0