Position statement on use of pharmacological combinations in a single pill for treatment of hypertension by Argentine Federation of Cardiology (FAC) and Argentine Society of Hypertension (SAHA)

Primer Autor
Renna, Nicolas
Co-autores
Piskorz, Daniel
Stisman, Diego
Martinez, Diego
Lescano, Ludmila
Vissani, Sergio
Espeche, Walter
Marquez, Diego
Parodi, Roberto
Naninni, Diego
Baroni, Marcos
Llanos, Daniel
Martinez, Rocio
Barochinner, Jessica
Staffieri, Gustavo
Lanas, Fernando
Velasquez, Monica
Marin, Marcos
Williams, Bryan
Ennis, Irene
Título
Position statement on use of pharmacological combinations in a single pill for treatment of hypertension by Argentine Federation of Cardiology (FAC) and Argentine Society of Hypertension (SAHA)
Editorial
SPRINGERNATURE
Revista
JOURNAL OF HUMAN HYPERTENSION
Lenguaje
en
Resumen
The present document provides scientific evidence reviewed and analysed by a group of specialist clinicians in hypertension that aims to give an insight into a pharmacological strategy to improve blood pressure control. Evidence shows that most hypertensive patients will need at least two drugs to achieve blood pressure goals. There is ample evidence showing that treatment adherence is inversely related to the number of drugs taken. Observational studies show that use of drug combinations to initiate treatment reduces the time to reach the treatment goal and reduces CVD, especially with single pill combinations (SPCs). This work, based on recommendations of the Argentine Federation of Cardiology and Argentine Society of Hypertension as a reference, aims to review the more recent evidence on SPC, and to serve as guidelines for health professionals in their clinical practice and to the wider use of SPCs for the treatment of hypertension. Evidence from clinical trials on the effectiveness and adverse effects of using SPCs are provided. An analysis is also made of the main contributions of SPCs in special populations, e.g., elderly and diabetic patients, and its use in high risk and resistant hypertension. The effects of SPCs on hypertensive-mediated organ damage is also examined. Finally, we provide some aspects to consider when choosing treatments in the economic context of Latin-America for promoting the most efficient use of resources in a scarce environment and to provide quality information to decision makers to formulate safe, cost-effective, and patient-centered health policies. Finally, future perspectives and limitations in clinical practice are also discussed.
Fecha Publicación
2023
Tipo de Recurso
artículo de revisión
Derecho de Acceso
registro bibliográfico
doi
10.1038/s41371-021-00557-w
Formato Recurso
PDF
Palabras Claves
Hypertension-drug therapy
Ubicación del archivo
Categoría OCDE
Sistema cardiovascular y cardiología
Sistema Cardiovascular y Cardiaco
Farmacología y Farmacia
Medicina General e Interna
Materias
hipertensión - tratamiento farmacologico
Página de inicio (Recomendado-único)
438.0
Página final (Recomendado-único)
448
Identificador del recurso (Mandatado-único)
artículo de revisión
Versión del recurso (Recomendado-único)
versión publicada
Derechos de acceso
metadata
Access Rights
metadata
Id de Web of Science
WOS:000658109100002
ISSN
0950-9240
Categoría WOS
Sistema cardiovascular y cardiología
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