Repositorio UFRO · Omeka S

Design of a separation process for natural 2-phenylethanol with solvent selection based on safety criteria

Primer Autor	Lopez-Molina, Antioco
Co-autores	Chacon-Izquierdo, Alejandro Magdaleno-Cruz, Ana E. Conde-Baez, Laura Mas-Hernandez, Elizabeth Conde-Mejia, Carolina
Título	Design of a separation process for natural 2-phenylethanol with solvent selection based on safety criteria
Editorial	WILEY
Revista	JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
Lenguaje	en
Resumen	BACKGROUND: In the past, process safety has improved safety issues in chemical plants, today, it is essential to consider safety aspects in any process plant. Furthermore, the production of value-added products through biotechnological methods has increased, and safety is usually not considered in this kind of process design. The biotechnological production of 2-phenylethanol (2-PE) has been studied at a laboratory scale. However, before considering industrial-scale production, it is necessary to design an efficient and safe purification process to maintain the quality characteristics of 2-PE. This work proposes a separation process for natural 2-PE (which was obtained from whey fermentation) and evaluates its safety and economic aspects. RESULTS: This process is based on liquid-liquid extraction. The feed stream consists of an aqueous mixture with 0.095 wt% of 2-PE and 1.54 wt% of ethanol. The conceptual design was implemented in the simulator Aspen Plus V.10. The bioprocess safety index (BPSI) was used to find the hazardous process streams for the safety evaluation. CONCLUSION: The 2-PE separation showed an overall recovery of 99.54% and a purity of 99.67 wt% in the product stream. The process streams identified as hazardous are the extract and solvent recycling streams. The utility and operating cost per separated kilogram of 2-PE are USD 0.658 kg(-1) and USD 14.48 kg(-1), respectively. The industrial-scale implementation of 2-PE bioproduction shows positive potential. (c) 2022 Society of Chemical Industry (SCI).
Fecha Publicación	2022
Tipo de Recurso	artículo original
Derecho de Acceso	registro bibliográfico
doi	10.1002/jctb.7081
Formato Recurso	PDF
Palabras Claves	liquid-liquid extraction process design residues simulation
Ubicación del archivo	http://dx.doi.org/10.1002/jctb.7081
Categoría OCDE	Biotecnología y Microbiología Aplicada Química Ingeniería Biotecnología Relacionada con la Salud Química Analítica Tecnología de Modificación Genética
Materias	extracción líquido-líquido diseño de procesos residuos simulación
Página de inicio (Recomendado-único)	2103.0
Página final (Recomendado-único)	2108
Identificador del recurso (Mandatado-único)	artículo original
Versión del recurso (Recomendado-único)	versión publicada
Derechos de acceso	metadata
Access Rights	metadata
Id de Web of Science	WOS:000782584300001
ISSN	0268-2575
Categoría WOS	Biotecnología y Microbiología Aplicada Química Ingeniería Ciencias de la Información y Bioinformática
Referencia del Financiador (Mandatado si es aplicable-repetible)	PRODEP UJAT-PTC-293 ANID FONDECYT 3200839