Effectiveness of mRNA, protein subunit vaccine and viral vectors vaccines against SARS-CoV-2 in people over 18 years old: a systematic review

Primer Autor
Sandoval, Cristian
Co-autores
Guerrero, Daniela
Munoz, Joham
Godoy, Karina
Souza-Mello, Vanessa
Farias, Jorge
Título
Effectiveness of mRNA, protein subunit vaccine and viral vectors vaccines against SARS-CoV-2 in people over 18 years old: a systematic review
Editorial
TAYLOR & FRANCIS LTD
Revista
EXPERT REVIEW OF VACCINES
Lenguaje
en
Resumen
Introduction: Vaccines prevent disease and disability, save lives and represent a good assessment of health interventions. Several systematic reviews on the efficacy and effectiveness of COVID-19 vaccines have been published, but the immunogenicity and safety of these vaccines should also be addressed. Areas covered: This systemic investigation sought to explain the efficacy, immunogenicity, and safety of new vaccination technologies against SARS-CoV-2 in people over 18 years old. Original research studying the effectiveness on mRNA, protein subunit vaccines, and viral vector vaccines against SARS-CoV-2 in people over 18 years old was analyzed. Several databases (Web of Science, Scopus, MEDLINE and EMBASE) were searched between 2012 and November 2022 for English-language papers using text and MeSH terms related to SARS-CoV-2, mechanism, protein subunit vaccine, viral vector, and mRNA. The protocol was registered on PROSPERO, CRD42022341952. Study quality was assessed using the NICE methodology. We looked at a total of six original articles. All studies gathered and presented quantitative data. Expert opinion: Our results suggest that new vaccinations could have more than 90% efficacy against SARS-CoV-2, regardless of the technology used. Furthermore, adverse reactions go from mild to moderate, and good immunogenicity can be observed for all vaccine types.
Fecha Publicación
2023
Tipo de Recurso
artículo de revisión
doi
10.1080/14760584.2023.2156861
Formato Recurso
PDF
Palabras Claves
Coronavirus
COVID vaccines
number of doses
vaccination
vaccine efficacy
vaccine platforms
Ubicación del archivo
Categoría OCDE
Inmunología
Materias
Coronavirus
Vacunas para COVID-19
número de dosis
vacunación
eficacia de la vacuna
plataformas de vacunas
Página de inicio (Recomendado-único)
35.0
Página final (Recomendado-único)
53
Identificador del recurso (Mandatado-único)
artículo de revisión
Versión del recurso (Recomendado-único)
versión publicada
License
CC BY 4.0
Condición de la licencia (Recomendado-repetible)
CC BY 4.0
Derechos de acceso
acceso abierto
Access Rights
acceso abierto
Id de Web of Science
WOS:000899564300001
ISSN
1476-0584
Tipo de ruta
Verde# dorado
Categoría WOS
Inmunología
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