Three-stage sequential supercritical extraction in fixed bed extractor to obtain bioactive compounds from Leptocarpha rivularis leaves
| Primer Autor |
Uquiche, Edgar
|
| Co-autores |
Aviles, Jorge
Marillan, Claudia
Quevedo-Leon, Roberto
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| Título |
Three-stage sequential supercritical extraction in fixed bed extractor to obtain bioactive compounds from Leptocarpha rivularis leaves
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| Editorial |
ELSEVIER
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| Revista |
JOURNAL OF APPLIED RESEARCH ON MEDICINAL AND AROMATIC PLANTS
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| Lenguaje |
en
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| Resumen |
This work studied sequential supercritical extraction to obtain extracts from L. rivularis leaves. Extraction assays were carried out in three stages at 40 or 70?, with stage 1: 20 MPa with CO2, stage 2: 40 MPa with CO2, and stage 3: 40 MPa with ethanol-modified CO2 (5% wt.). The total extraction yield was higher at 70 ? (41.77 g/kg d.s.) than at 40?(32.57 g/kg d.s.). The total content of terpenes and flavonoids and the ability of the extracts to inhibit the a-amylase and a-glucosidase enzymes were measured. At 40 C the stage 1 extract had a greater inhibition effect on a-glucosidase and the stage 2 extract a greater inhibition effect on a-amylase. Sequential supercritical extraction was properly modeled using a diffusion model based on Fick's second law, and an effective diffusion coefficient was determined for each stage. Sequential supercritical extraction can be a method to increase the extraction of bioactive compounds.
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| Fecha Publicación |
2023
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| Tipo de Recurso |
artículo original
|
| doi |
10.1016/j.jarmap.2023.100460
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| Formato Recurso |
PDF
|
| Palabras Claves |
Supercritical extraction
Leptocarpha rivularis
Sequential extraction
alpha-amylase
alpha-glucosidase
Diffusion model
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| Ubicación del archivo | |
| Categoría OCDE |
Ciencias de las plantas
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| Materias |
Extracción supercrítica
Leptocarpha rivularis
Extracción secuencial
alfa-amilasa
alfa-glucosidasa
Modelo de difusión
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| Identificador del recurso (Mandatado-único) |
artículo original
|
| Versión del recurso (Recomendado-único) |
versión publicada
|
| Derechos de acceso |
metadata
|
| Access Rights |
metadata
|
| Id de Web of Science |
WOS:000995584200001
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| Tipo de ruta |
hibrida
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| Categoría WOS |
Ciencias de las plantas
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| Referencia del Financiador (Mandatado si es aplicable-repetible) |
ANID-FONDECYT 1170841
ANID 22182141
ANID 21201441
ANID FONDECYT 1170841
|
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