Repositorio
Institucional

Hystad, Perry

Wang, Ying

Duong, MyLinh

Brauer, Michael

Rangarajan, Sumathy

Dans, Antonio

Lanas, Fernando

Lopez-Jaramillo, Patricio

Puoane, Thandi

Yeates, Karen

Chifamba, Jephat

Yusuf, Rita

Liu, Zhiguang

Li, Yang

Tse, Lap Ah

Mohan, Deepa

Gupta, Rajeev

Nair, Sanjeev

Lakshmi, P. V. M.

Iqbal, Romaina

Anto, Taniya

Yusuf, Salim

Household Air Pollution and Adult Lung Function Change, Respiratory Disease, and Mortality across Eleven Low- and Middle-Income Countries from the PURE Study

US DEPT HEALTH HUMAN SCIENCES PUBLIC HEALTH SCIENCE

ENVIRONMENTAL HEALTH PERSPECTIVES

en

BACKGROUND: Globally, household air pollution (HAP) is a major environmental hazard that affects respiratory health. However, few studies have examined associations between HAP and lung function decline and respiratory disease and mortality. METHODS: We used data from the Prospective Urban and Rural Epidemiology study and examined adults residing in 240 rural communities in 11 low-and middle-income countries where HAP from cooking with solid fuels is common. Spirometry was conducted for 28,574 individuals at baseline and 12,489 individuals during follow-up (mean of 8 y between spirometry measures). In cross-sectional analyses, we compared lung function measurements [forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), and FEV1/FVC ratio] in those who used solid fuels for cooking in comparison with clean fuels. Using repeated measurements of lung function, we examined the percent change in lung function measures per year, comparing individuals by baseline fuel type and individuals who used solid fuels at baseline but switched to clean fuels during follow-up. We also examined associations with prospective health events (any respiratory diseases, respiratory disease hospitalizations, and all -cause mortality). RESULTS: In adjusted cross-sectional models, use of solid fuel in comparison with clean fuels was associated with lower FEV1 of -17.5 mL (95% CI: -32.7, -2.3) and FVC of -14.4 mL (95% CI: -32.0, 3.2), but not FEV1/FVC. In longitudinal analyses, individuals who switched from solid fuels to clean cooking fuels during follow-up (n = 3,901, 46% of those using solid fuel at baseline), showed no differences in the annual rate of change in FEV1 or FVC, but had small improvements in FEV1/FVC change (0.2% per year, 95% CI: 0.03, 0.3). Individuals who switched from solid to clean fuels had a decreased hazard ratio for respiratory events of 0.76 (95% CI: 0.57, 1.00) in comparison with persistent solid fuel users, which was not attenuated by lung function measures. CONCLUSION: We observed modest associations between HAP exposure and lung function, lung function change, and respiratory disease and mortal-ity. https://doi.org/10.1289/EHP11179

2023

artículo original

10.1289/EHP11179

PDF

Adult

Air Pollution

Air Pollution, Indoor / analysis

Cooking

Cross-Sectional Studies

Developing Countries

Humans

Lung

Respiratory Tract Diseases

Ciencias Ambientales y Ecología

Salud Pública, Ambiental y Ocupacional

Toxicología

Adulto

contaminación del aire

Contaminación del aire en interiores / análisis

Cocinando

Estudios Transversales

Países en desarrollo

Humanos

Pulmón

Enfermedades del tracto respiratorio

artículo original

versión publicada

acceso abierto

acceso abierto

WOS:000996363400003

0091-6765

Verde# dorado

Ciencias Ambientales y Ecología

Salud Pública, Ambiental y Ocupacional

Toxicología

NIH DP5OD019850

CIHR 136893