Repositorio
Institucional

Rojas, Claudio

Manterola, Carlos

Rivadeneira, Josue

Pogue, Spencer D.

Morphology of Echinococcus granulosus Protoscolex

SOC CHILENA ANATOMIA

INTERNATIONAL JOURNAL OF MORPHOLOGY

en

Echinococcus granulosus (E. granulosus), is a tapeworm that spreads between intermediate and definitive hosts through the ingestion of fecal matter contaminated with the parasite's eggs. The life cycle consists of differentiation from eggs to oncospheres to embryos, which eventually form cysts in organs like the liver, lungs and others. Within these cysts are protoscolices, an intermediate stage of the parasite which develop into adult tapeworms once they infect their definitive hosts. When these hydatid cysts form in humans, it is known as Cystic Echinococcosis (CE). This disease is treated through surgical excision of the cysts and or chemotherapy with benzimidazole compounds. Understanding the morphology of the intermediate developmental stage of E. granulosus, protoscolex stage, can allow researchers to identify defining structural changes and protein functions that could be used to develop treatment modalities for CE. Unique characteristics in the tegumental surface during the protoescolex stage and proteins associated with cyst fertility have all been identified in previous research studies and bring researchers closer to understanding the underlying mechanisms of E. granulosus development, and consequently, means to disrupt it to achieve better control of the disease.

2023

artículo original

10.4067/S0717-95022023000200646

PDF

Echinococcus granulosus

Echinococcosis

Cystic Echinococcosis

Hydatid Cyst

Protoscolex

Morphology

Anatomía y Morfología

Echinococcus granulosus

Equinococosis

Equinococosis Quística

Quiste hidatídico

Protoscólex

Morfología

646.0

653

artículo original

versión publicada

acceso abierto

acceso abierto

WOS:001001066200047

0717-9502

verde# dorado

Anatomía y Morfología