Repositorio UFRO · Omeka S

Histological Effect of Platelet-Rich Plasma on Temporomandibular Joint Osteoarthritis: Systematic Review in Animal Models

Primer Autor	Iturriaga, Veronica
Co-autores	Wen, Schilin Torres, Hector Gonzalez, Javier Thomas, Davis C. Bornhardt, Thomas
Título	Histological Effect of Platelet-Rich Plasma on Temporomandibular Joint Osteoarthritis: Systematic Review in Animal Models
Editorial	SOC CHILENA ANATOMIA
Revista	INTERNATIONAL JOURNAL OF MORPHOLOGY
Lenguaje	en
Resumen	The aim of this systematic review was to assess the histological effects of platelet-rich plasma (PRP) on temporomandibular joint osteoarthritis (TMJ-OA) in animal models. A systematic search was performed using PubMed, WoS, EMBASE, Science Direct and SCOPUS databases. The inclusion criteria were experimental studies in animal models that evaluated the use of PRP as a treatment for TMJ-OA with or without arthrocentesis/arthroscopy. Comparison was made to a healthy control group or to other treatment. The variables evaluated were the histological effects of the treatments, characteristics of the primary articles, characteristics of the sample studied and the risk of bias. The systematic search identified 120 studies. Eventually 5 studies were included in the analysis. Four of the studies showed a statistically significant repair in joint tissues and improvement of cartilage thickness in animals treated with PRP. The global risk of bias was unclear. The results of this systematic review suggest that PRP treatment in TMJ-OA has benefits at the histological level in cartilage, articular disc and articular bone tissue in animal models. However, due to the low number of studies and the risk of bias, further research is needed to recommend its use.
Fecha Publicación	2023
Tipo de Recurso	artículo de revisión
doi	10.4067/S0717-95022023000200660
Formato Recurso	PDF
Palabras Claves	Platelet-rich plasma Temporomandibular disorders Temporomandibular joint Osteoarthritis Growth factors Systematic review
Ubicación del archivo	http://dx.doi.org/10.4067/S0717-95022023000200660
Categoría OCDE	Anatomía y Morfología
Materias	Plasma rico en plaquetas Trastornos temporomandibulares Articulación temporomandibular Osteoartritis Factores de crecimiento Revisión sistemática
Página de inicio (Recomendado-único)	660.0
Página final (Recomendado-único)	667
Identificador del recurso (Mandatado-único)	artículo de revisión
Versión del recurso (Recomendado-único)	versión publicada
Derechos de acceso	acceso abierto
Access Rights	acceso abierto
Id de Web of Science	WOS:001001066200049
ISSN	0717-9502
Tipo de ruta	verde# dorado
Categoría WOS	Anatomía y Morfología
Referencia del Financiador (Mandatado si es aplicable-repetible)	UFRO DI20-0018