Histological Effect of Platelet-Rich Plasma on Temporomandibular Joint Osteoarthritis: Systematic Review in Animal Models

Primer Autor
Iturriaga, Veronica
Co-autores
Wen, Schilin
Torres, Hector
Gonzalez, Javier
Thomas, Davis C.
Bornhardt, Thomas
Título
Histological Effect of Platelet-Rich Plasma on Temporomandibular Joint Osteoarthritis: Systematic Review in Animal Models
Editorial
SOC CHILENA ANATOMIA
Revista
INTERNATIONAL JOURNAL OF MORPHOLOGY
Lenguaje
en
Resumen
The aim of this systematic review was to assess the histological effects of platelet-rich plasma (PRP) on temporomandibular joint osteoarthritis (TMJ-OA) in animal models. A systematic search was performed using PubMed, WoS, EMBASE, Science Direct and SCOPUS databases. The inclusion criteria were experimental studies in animal models that evaluated the use of PRP as a treatment for TMJ-OA with or without arthrocentesis/arthroscopy. Comparison was made to a healthy control group or to other treatment. The variables evaluated were the histological effects of the treatments, characteristics of the primary articles, characteristics of the sample studied and the risk of bias. The systematic search identified 120 studies. Eventually 5 studies were included in the analysis. Four of the studies showed a statistically significant repair in joint tissues and improvement of cartilage thickness in animals treated with PRP. The global risk of bias was unclear. The results of this systematic review suggest that PRP treatment in TMJ-OA has benefits at the histological level in cartilage, articular disc and articular bone tissue in animal models. However, due to the low number of studies and the risk of bias, further research is needed to recommend its use.
Fecha Publicación
2023
Tipo de Recurso
artículo de revisión
doi
10.4067/S0717-95022023000200660
Formato Recurso
PDF
Palabras Claves
Platelet-rich plasma
Temporomandibular disorders
Temporomandibular joint
Osteoarthritis
Growth factors
Systematic review
Ubicación del archivo
Categoría OCDE
Anatomía y Morfología
Materias
Plasma rico en plaquetas
Trastornos temporomandibulares
Articulación temporomandibular
Osteoartritis
Factores de crecimiento
Revisión sistemática
Página de inicio (Recomendado-único)
660.0
Página final (Recomendado-único)
667
Identificador del recurso (Mandatado-único)
artículo de revisión
Versión del recurso (Recomendado-único)
versión publicada
Derechos de acceso
acceso abierto
Access Rights
acceso abierto
Id de Web of Science
WOS:001001066200049
ISSN
0717-9502
Tipo de ruta
verde# dorado
Categoría WOS
Anatomía y Morfología
Referencia del Financiador (Mandatado si es aplicable-repetible)
UFRO DI20-0018
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