OncoCardioDB: a public and curated database of molecular information in onco-cardiology/cardio-oncology

Primer Autor
Domingo, Juan
Co-autores
Dura, Esther
Riffo-Campos, Angela L.
Título
OncoCardioDB: a public and curated database of molecular information in onco-cardiology/cardio-oncology
Editorial
OXFORD UNIV PRESS
Revista
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
Lenguaje
en
Resumen
Numerous studies have been published which, separately, investigate the influence of molecular features on oncological and cardiac pathologies. Nevertheless, the relationship between both families of diseases at the molecular level is an emerging area within oncocardiology/cardio-oncology.This paper presents a new open-source database that aims to organize the curated information concerning the molecular features validated in patients involved in both cancer and cardiovascular diseases. Entities like gene, variation, drug, study and others are modelled as objects of a database which is populated with curated information from 83 papers identified by systematic literature searched for up to 2021. Researchers will discover new connections among them to validate hypotheses or suggest new ones. Special care has been taken to use standard nomenclature for genes, pathologies and all the objects for which accepted conventions exist. The database can be consulted via the web with a system of simplified queries, but it also accepts any query. It will be updated and refined with the incorporation of new studies as they become available.
Fecha Publicación
2023
Tipo de Recurso
artículo original
doi
10.1093/database/baad029
Formato Recurso
PDF
Palabras Claves
Cardiology
Cardiovascular Diseases / genetics
Databases, Factual
Humans
Medical Oncology
Neoplasms / genetics
Ubicación del archivo
Categoría OCDE
Biología Matemática y Computacional
Materias
Cardiología
Enfermedades Cardiovasculares/genética
Bases de datos fácticas
Humanos
Oncologia medica
Neoplasias / genética
Identificador del recurso (Mandatado-único)
artículo original
Versión del recurso (Recomendado-único)
versión publicada
License
CC BY 4.0
Condición de la licencia (Recomendado-repetible)
CC BY 4.0
Derechos de acceso
acceso abierto
Access Rights
acceso abierto
Id de Web of Science
WOS:000985169300002
ISSN
1758-0463
Tipo de ruta
verde# dorada
Categoría WOS
Biología Matemática y Computacional
Referencia del Financiador (Mandatado si es aplicable-repetible)
PID2020-117114GB-I00
MCINN AEI/10.13039/501100011033
ANID-FONDECYT 3180486
UFRO DIUFRO DI22-0014
ANID FONDECYT 3180486
UFRO DI22-0014
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