Repositorio
Institucional

Santibanez, M

Fuentealba, M.

Bodineau, C.

Gadolinium dose enhancement determination by unlaminated EBT3 films irradiated with 192Ir brachytherapy source

PERGAMON-ELSEVIER SCIENCE LTD

RADIATION PHYSICS AND CHEMISTRY

en

In this work, Gafchromic & REG, EBT3 films were carefully delaminated and resealed with a thin mylar film of 12 & mu,m for implementing accuracy measurements of Gd dose enhancement by a192Ir brachytherapy source. The inter-vened dosimeters were previously characterized in terms of their quality intervention (mechanical damage and dosimetry modification). The dose enhancement measurements were implemented in a phantom formed by a set of acrylic slabs of 30 x 30 x 0.5 cm3 machined to contain in the central axis 2 vials of 1.25 x 1.25 x 4.5 cm3 which were filled with a 20 mg/ml solution of Gd agents and with water simulating a tumoral phantom doped and undoped with Gd. In the center of the phantom, a machined acrylic slab was placed to introduce the 2.5 mm flexible guide of GammaMedplus iX equipment to position the source. Fragments of delaminated and resealed EBT3 of 0.9 x 4 cm2 were placed inside the second vial and 0.5 cm away from it, at 1.95 cm and 3.55 cm from the radioactive source respectively, to measure simultaneously the tumor dose enhancement and the radiation shielding produced at a proximal zone. CT images of the phantom were taken to prescribe 5 Gy to 1.95 cm (EBT3 film position) using a Varian BrachyVisionTM planning system. Films were read out by a flatbed scanner Epson V750 PRO, 48 h after irradiation. The measurements in both tumor and healthy tissue were repeated ten times in each condition to analyze the uncertainties of the complete experimental realization. The results showed vari-ations in the response of the intervened dosimeters, less than 1.7% for the range of interest and average fluc-tuations in the readout of 4.6%. The implemented dosimeter showed the feasibility of measuring dose enhancement by 192Ir source of 13 & PLUSMN, 7% for the concentration studied. Additionally, radiation shielding up to 6% was obtained, consistent with what has been reported in the literature.

2023

artículo original

10.1016/j.radphyschem.2023.111103

PDF

Gd dose enhancement

Delaminated EBT3

EBT3 dosimetry

192Ir brachytherapy

Química

Ciencia y tecnología nucleares

Física

aumento de la dosis de Gd

EBT3 delaminado

dosimetría EBT3

192Braquiterapia por Ir

artículo original

versión publicada

metadata

metadata

WOS:001024491800001

0969-806X

verde / hibrido

Química

Ciencia y tecnología nucleares

Física

ANID-FONDECYT 1221000

UFRO DIUFRO DI21-0072

ANID FONDECYT 1221000

UFRO DI21-0072