Repositorio UFRO · Omeka S

Toward the use of mixed microbial cultures for the biological production of adipic and levulinic acid

Primer Autor	Pinto-Ibieta, Fernanda
Co-autores	Cea, Mara Serrano, Antonio Felissia, Fernando E. Area, Maria Cristina Cabrera, Francisco Ciudad, Gustavo
Título	Toward the use of mixed microbial cultures for the biological production of adipic and levulinic acid
Editorial	FRONTIERS MEDIA SA
Revista	FRONTIERS IN MICROBIOLOGY
Lenguaje	en
Resumen	Biological synthesis of high added-value compounds like adipic acid (AA), levulinic acid (LA), or polyhydroxybutyrate (PHB) using pure culture has been separately reported. However, pure culture requires sterile conditions and the use of specific carbon sources resulting in high operating costs. Different alternatives based on the use of mixed microbial cultures (MMC) have been explored to resolve this problem. MMC have been widely reported for the production of PHB, but scarcely reported for LA production and never for AA synthesis. This work presents a novel strategy for the co-production of AA LA, and PHB using MMC. The strategy consists in selecting an MMC producer of AA, LA and PHB from an inoculum obtained from a wastewater treatment plant, which is then subjected to the feast and famine culture strategy in a sequential batch reactor, coupled with a batch reactor step to enhance the accumulation of AA and LA. The results showed that the MMC could produce a 16 & PLUSMN, 2, 23 & PLUSMN, 1 and 5 & PLUSMN, %1 (g compound/g volatile solids) of AA, LA and PHB, respectively, using a non-fermented residual biomass rich in pentose, namely synthetic hemicellulose hydrolysate (SHH) as the carbon source. These results contribute to generating future research to better understand and optimise the biosynthesis of these compounds by MMC.
Fecha Publicación	2023
Tipo de Recurso	artículo original
doi	10.3389/fmicb.2023.1224543
Formato Recurso	PDF
Palabras Claves	adipic acid levulinic acid mixed microbial cultures (MMC) hemicellulose hydrolysate feast and famine
Ubicación del archivo	http://dx.doi.org/10.3389/fmicb.2023.1224543
Categoría OCDE	Microbiología
Materias	acido adipico ácido levulínico cultivos microbianos mixtos (MMC) hidrolizado de hemicelulosa fiesta y hambruna
Identificador del recurso (Mandatado-único)	artículo original
Versión del recurso (Recomendado-único)	versión publicada
License	CC BY 4.0
Condición de la licencia (Recomendado-repetible)	CC BY 4.0
Derechos de acceso	acceso abierto
Access Rights	acceso abierto
Id de Web of Science	WOS:001026432600001
Tipo de ruta	verde# dorado
Categoría WOS	Microbiología
Referencia del Financiador (Mandatado si es aplicable-repetible)	ANID-FONDECYT 3210626 ANID FONDECYT 3210626