Toward the use of mixed microbial cultures for the biological production of adipic and levulinic acid
| Primer Autor |
Pinto-Ibieta, Fernanda
|
| Co-autores |
Cea, Mara
Serrano, Antonio
Felissia, Fernando E.
Area, Maria Cristina
Cabrera, Francisco
Ciudad, Gustavo
|
| Título |
Toward the use of mixed microbial cultures for the biological production of adipic and levulinic acid
|
| Editorial |
FRONTIERS MEDIA SA
|
| Revista |
FRONTIERS IN MICROBIOLOGY
|
| Lenguaje |
en
|
| Resumen |
Biological synthesis of high added-value compounds like adipic acid (AA), levulinic acid (LA), or polyhydroxybutyrate (PHB) using pure culture has been separately reported. However, pure culture requires sterile conditions and the use of specific carbon sources resulting in high operating costs. Different alternatives based on the use of mixed microbial cultures (MMC) have been explored to resolve this problem. MMC have been widely reported for the production of PHB, but scarcely reported for LA production and never for AA synthesis. This work presents a novel strategy for the co-production of AA LA, and PHB using MMC. The strategy consists in selecting an MMC producer of AA, LA and PHB from an inoculum obtained from a wastewater treatment plant, which is then subjected to the feast and famine culture strategy in a sequential batch reactor, coupled with a batch reactor step to enhance the accumulation of AA and LA. The results showed that the MMC could produce a 16 & PLUSMN, 2, 23 & PLUSMN, 1 and 5 & PLUSMN, %1 (g compound/g volatile solids) of AA, LA and PHB, respectively, using a non-fermented residual biomass rich in pentose, namely synthetic hemicellulose hydrolysate (SHH) as the carbon source. These results contribute to generating future research to better understand and optimise the biosynthesis of these compounds by MMC.
|
| Fecha Publicación |
2023
|
| Tipo de Recurso |
artículo original
|
| doi |
10.3389/fmicb.2023.1224543
|
| Formato Recurso |
PDF
|
| Palabras Claves |
adipic acid
levulinic acid
mixed microbial cultures (MMC)
hemicellulose hydrolysate
feast and famine
|
| Ubicación del archivo | |
| Categoría OCDE |
Microbiología
|
| Materias |
acido adipico
ácido levulínico
cultivos microbianos mixtos (MMC)
hidrolizado de hemicelulosa
fiesta y hambruna
|
| Identificador del recurso (Mandatado-único) |
artículo original
|
| Versión del recurso (Recomendado-único) |
versión publicada
|
| License |
CC BY 4.0
|
| Condición de la licencia (Recomendado-repetible) |
CC BY 4.0
|
| Derechos de acceso |
acceso abierto
|
| Access Rights |
acceso abierto
|
| Id de Web of Science |
WOS:001026432600001
|
| Tipo de ruta |
verde# dorado
|
| Categoría WOS |
Microbiología
|
| Referencia del Financiador (Mandatado si es aplicable-repetible) |
ANID-FONDECYT 3210626
ANID FONDECYT 3210626
|
cienciaabierta.ufro.cl
ciencia.abierta@ufrontera.cl