Repositorio UFRO · Omeka S

Antibacterial Films of Silver Nanoparticles Embedded into Carboxymethylcellulose/Chitosan Multilayers on Nanoporous Silicon: A Layer-by-Layer Assembly Approach Comparing Dip and Spin Coating

Primer Autor	Naveas, Nelson
Co-autores	Pulido, Ruth Torres-Costa, Vicente Agullo-Rueda, Fernando Santibanez, Mauricio Malano, Francisco Recio-Sanchez, Gonzalo Garrido-Miranda, Karla A. Manso-Silvan, Miguel Hernandez-Montelongo, Jacobo
Título	Antibacterial Films of Silver Nanoparticles Embedded into Carboxymethylcellulose/Chitosan Multilayers on Nanoporous Silicon: A Layer-by-Layer Assembly Approach Comparing Dip and Spin Coating
Editorial	MDPI
Revista	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Lenguaje	en
Resumen	The design and engineering of antibacterial materials are key for preventing bacterial adherence and proliferation in biomedical and household instruments. Silver nanoparticles (AgNPs) and chitosan (CHI) are broad-spectrum antibacterial materials with different properties whose combined application is currently under optimization. This study proposes the formation of antibacterial films with AgNPs embedded in carboxymethylcellulose/chitosan multilayers by the layer-by-layer (LbL) method. The films were deposited onto nanoporous silicon (nPSi), an ideal platform for bioengineering applications due to its biocompatibility, biodegradability, and bioresorbability. We focused on two alternative multilayer deposition processes: cyclic dip coating (CDC) and cyclic spin coating (CSC). The physicochemical properties of the films were the subject of microscopic, microstructural, and surface-interface analyses. The antibacterial activity of each film was investigated against Escherichia coli (Gram-negative) and Staphylococcus aureus (Gram-positive) bacteria strains as model microorganisms. According to the findings, the CDC technique produced multilayer films with higher antibacterial activity for both bacteria compared to the CSC method. Bacteria adhesion inhibition was observed from only three cycles. The developed AgNPs-multilayer composite film offers advantageous antibacterial properties for biomedical applications.
Fecha Publicación	2023
Tipo de Recurso	artículo original
doi	10.3390/ijms241310595
Formato Recurso	PDF
Palabras Claves	antibacterial films carboxymethylcellulose chitosan silver nanoparticles nanoporous silicon composite material layer-by-layer
Ubicación del archivo	http://dx.doi.org/10.3390/ijms241310595
Categoría OCDE	Bioquímica y biología molecular Química
Materias	películas antibacterianas carboximetilcelulosa quitosano nanopartículas de plata silicio nanoporoso material compuesto capa por capa
Identificador del recurso (Mandatado-único)	artículo original
Versión del recurso (Recomendado-único)	versión publicada
License	CC BY 4.0
Condición de la licencia (Recomendado-repetible)	CC BY 4.0
Derechos de acceso	acceso abierto
Access Rights	acceso abierto
Id de Web of Science	WOS:001031083500001
ISSN	1661-6596
Tipo de ruta	verde# dorado
Categoría WOS	Bioquímica y biología molecular Química
Referencia del Financiador (Mandatado si es aplicable-repetible)	ANID-FONDECYT 11180395 CONICYT PFCHA 21172001 CONICYT PFCHA/DOCTORADO 21151648 MICINN USAMPSA PID2020-112770RB-C22 ANID FONDECYT 11180395