Antimicrobial Activity of Selenium Nanoparticles (SeNPs) against Potentially Pathogenic Oral Microorganisms: A Scoping Review
| Primer Autor |
Sans-Serramitjana, Eulalia
|
| Co-autores |
Obreque, Macarena
Munoz, Fernanda
Zaror, Carlos
Mora, Maria de La Luz
Vinas, Miguel
Betancourt, Pablo
|
| Título |
Antimicrobial Activity of Selenium Nanoparticles (SeNPs) against Potentially Pathogenic Oral Microorganisms: A Scoping Review
|
| Editorial |
MDPI
|
| Revista |
PHARMACEUTICS
|
| Lenguaje |
en
|
| Resumen |
Biofilms are responsible for the most prevalent oral infections such as caries, periodontal disease, and pulp and periapical lesions, which affect the quality of life of people. Antibiotics have been widely used to treat these conditions as therapeutic and prophylactic compounds. However, due to the emergence of microbial resistance to antibiotics, there is an urgent need to develop and evaluate new antimicrobial agents. This scoping review offers an extensive and detailed synthesis of the potential role of selenium nanoparticles (SeNPs) in combating oral pathogens responsible for causing infectious diseases. A systematic search was conducted up until May 2022, encompassing the MEDLINE, Embase, Scopus, and Lilacs databases. We included studies focused on evaluating the antimicrobial efficacy of SeNPs on planktonic and biofilm forms and their side effects in in vitro studies. The selection process and data extraction were carried out by two researchers independently. A qualitative synthesis of the results was performed. A total of twenty-two articles were considered eligible for this scoping review. Most of the studies reported relevant antimicrobial efficacy against C. albicans, S. mutans, E. faecalis, and P. gingivalis, as well as effective antioxidant activity and limited toxicity. Further research is mandatory to critically assess the effectiveness of this alternative treatment in ex vivo and in vivo settings, with detailed information about SeNPs concentrations employed, their physicochemical properties, and the experimental conditions to provide enough evidence to address the construction and development of well-designed and safe protocols.
|
| Fecha Publicación |
2023
|
| Tipo de Recurso |
artículo de revisión
|
| doi |
10.3390/pharmaceutics15092253
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| Formato Recurso |
PDF
|
| Palabras Claves |
selenium nanoparticles
antimicrobial activity
biofilm
planktonic state
oral pathogens
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| Ubicación del archivo | |
| Categoría OCDE |
Farmacología y farmacia
|
| Materias |
nanopartículas de selenio
actividad antimicrobiana
biopelícula
estado planctónico
patógenos orales
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| Identificador del recurso (Mandatado-único) |
artículo de revisión
|
| Versión del recurso (Recomendado-único) |
versión publicada
|
| License |
CC BY 4.0
|
| Condición de la licencia (Recomendado-repetible) |
CC BY 4.0
|
| Derechos de acceso |
acceso abierto
|
| Access Rights |
acceso abierto
|
| Id de Web of Science |
WOS:001077757800001
|
| Tipo de ruta |
verde# dorado
|
| Categoría WOS |
Farmacología y farmacia
|
| Referencia del Financiador (Mandatado si es aplicable-repetible) |
ANID-FONDECYT 3210302
UFRO DIUFRO DI21-0060.
ANID FONDECYT 3210302
UFRO DI21-0060
|
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