Repositorio UFRO · Omeka S

Insights into Co-Cultivation of Photosynthetic Microorganisms for Novel Molecule Discovery and Enhanced Production of Specialized Metabolites

Primer Autor	Rojas-Villalta, Dorian
Co-autores	Gomez-Espinoza, Olman Murillo-Vega, Francinie Villalta-Romero, Fabian Guerrero, Maritza Guillen-Watson, Rossy Nunez-Montero, Kattia
Título	Insights into Co-Cultivation of Photosynthetic Microorganisms for Novel Molecule Discovery and Enhanced Production of Specialized Metabolites
Editorial	MDPI
Revista	FERMENTATION-BASEL
Lenguaje	en
Resumen	Meso- and extremophilic microalgae and cyanobacteria have a wide range of biotechnological applications. However, the industrial demand for bioactive molecules and the redundancy of these molecules has resulted in a need for new methodologies for enhanced production and the discovery of specialized metabolites. Co-cultivation has been established as a promising approach to addressing these challenges. In this context, this work aimed to describe the state of the art of the co-cultivation method involving meso- and extremophilic photosynthetic microorganisms, as well as discuss the advantages, challenges, and limitations of this approach. Co-culture is defined as an ecology-driven method in which various symbiotic interactions involving cyanobacteria and microalgae can be used to explore new compounds and enhanced production. Promising results regarding new bioactive metabolite expression and increased production through co-cultivation-based research support that idea. Also, the metabolic diversity and evolutionary adaptations of photosynthetic microorganisms to thrive in extreme environments could improve the efficiency of co-cultivation by allowing the implementation of these microorganisms. However, the complexity of ecological interactions and lack of standardization for co-cultivation protocols are obstacles to its success and scientific validation. Further research in symbiotic interplays using -omics and genetic engineering, and predictive experimental designs for co-cultures are needed to overcome these limitations.
Fecha Publicación	2023
Tipo de Recurso	artículo de revisión
doi	10.3390/fermentation9110941
Formato Recurso	PDF
Palabras Claves	bioactive metabolites ecological interactions co-culture new bioprospecting algae
Ubicación del archivo	http://dx.doi.org/10.3390/fermentation9110941
Categoría OCDE	Biotecnología y microbiología aplicada Ciencia y tecnología de los alimentos
Materias	metabolitos bioactivos interacciones ecológicas cocultura nueva bioprospección algas
Identificador del recurso (Mandatado-único)	artículo de revisión
Versión del recurso (Recomendado-único)	versión publicada
License	CC BY 4.0
Condición de la licencia (Recomendado-repetible)	CC BY 4.0
Derechos de acceso	acceso abierto
Access Rights	acceso abierto
Id de Web of Science	WOS:001119834200001
Tipo de ruta	verde# dorado
Categoría WOS	Biotecnología y microbiología aplicada Ciencia y tecnología de los alimentos
Referencia del Financiador (Mandatado si es aplicable-repetible)	TEC