Repositorio UFRO · Omeka S

Effect of intermediate-term firewood smoke air pollution on cardiometabolic risk factors and inflammatory markers

Primer Autor	Lanas, Fernando
Co-autores	Saavedra, Nicolas Saavedra, Kathleen Hevia, Montserrat Seron, Pamela Salazar, Luis A.
Título	Effect of intermediate-term firewood smoke air pollution on cardiometabolic risk factors and inflammatory markers
Editorial	FRONTIERS MEDIA SA
Revista	FRONTIERS IN CARDIOVASCULAR MEDICINE
Lenguaje	en
Resumen	Background: Temuco is a city in Southern Chile with elevated levels of air pollution (AP), mainly due to using wood as combustion throughout the cold season. The study aimed to assess the differences in cardiometabolic risk factors, estimated cardiovascular risk, and blood level of inflammatory markers between high AP (HAP) and low AP (LAP) periods.Methods: A prospective panel study was conducted between January to September 2018. Air pollution was assessed by PM2.5 concentration. Ninety individuals from the general population were included in the study. Measurements were performed in the HAP and LAP, including medical history and lifestyle, physical activity assessment, physical exam, and fasting blood samples for glucose, lipids, and circulatory inflammatory mediators.Results: In the high air pollution period, systolic blood pressure was 3 mmHg higher (p = 0.05). HDL-cholesterol was 14.2 mg/dl lower (p < 0.001), Framingham risk score increased from 14.5 to 18.0 (p < 0.001), and highly significant lower levels of interleukins, MCP1, MMP1, MMP2, sICAM, and svCAM were observed.Conclusions: HAP was associated with increased cardiometabolic risk factors and estimated cardiovascular risk. However, a lower level of circulating acute inflammatory molecules was observed. Inflammatory molecules blood levels were not associated with changes in cardiometabolic risk factors.
Fecha Publicación	2023
Tipo de Recurso	artículo original
doi	10.3389/fcvm.2023.1252542
Formato Recurso	PDF
Palabras Claves	air pollution cardiometabolic risk factors inflammatory cytokines cold weather cardiovascular risk
Ubicación del archivo	http://dx.doi.org/10.3389/fcvm.2023.1252542
Categoría OCDE	Sistema cardiovascular y cardiología
Materias	contaminación del aire factores de riesgo cardiometabólico citoquinas inflamatorias clima frío riesgo cardiovascular
Identificador del recurso (Mandatado-único)	artículo original
Versión del recurso (Recomendado-único)	versión publicada
License	CC BY 4.0
Condición de la licencia (Recomendado-repetible)	CC BY 4.0
Derechos de acceso	acceso abierto
Access Rights	acceso abierto
Id de Web of Science	WOS:001115787200001
ISSN	2297-055X
Tipo de ruta	verde# dorado
Categoría WOS	Sistema cardiovascular y cardiología
Referencia del Financiador (Mandatado si es aplicable-repetible)	CONICYT-FONDECYT ANID FONDECYT