Repositorio UFRO · Omeka S

MicroRNAs as Potential Biomarkers of Environmental Exposure to Polycyclic Aromatic Hydrocarbons and Their Link with Inflammation and Lung Cancer

Primer Autor	Letelier, Pablo
Co-autores	Saldias, Rolando Loren, Pia Riquelme, Ismael Guzman, Neftali
Título	MicroRNAs as Potential Biomarkers of Environmental Exposure to Polycyclic Aromatic Hydrocarbons and Their Link with Inflammation and Lung Cancer
Editorial	MDPI
Revista	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Lenguaje	en
Resumen	Exposure to atmospheric air pollution containing volatile organic compounds such as polycyclic aromatic hydrocarbons (PAHs) has been shown to be a risk factor in the induction of lung inflammation and the initiation and progression of lung cancer. MicroRNAs (miRNAs) are small single-stranded non-coding RNA molecules of similar to 20-22 nucleotides that regulate different physiological processes, and their altered expression is implicated in various pathophysiological conditions. Recent studies have shown that the regulation of gene expression of miRNAs can be affected in diseases associated with outdoor air pollution, meaning they could also be useful as biomarkers of exposure to environmental pollution. In this article, we review the published evidence on miRNAs in relation to exposure to PAH pollution and discuss the possible mechanisms that may link these compounds with the expression of miRNAs.
Fecha Publicación	2023
Tipo de Recurso	artículo de revisión
doi	10.3390/ijms242316984
Formato Recurso	PDF
Palabras Claves	polycyclic aromatic hydrocarbons pulmonary cancer lung cancer microRNAs particulate matter
Ubicación del archivo	http://dx.doi.org/10.3390/ijms242316984
Categoría OCDE	Bioquímica y biología molecular Química
Materias	hidrocarburos aromáticos policíclicos cáncer de pulmón microARN materia particular
Versión del recurso (Recomendado-único)	versión publicada
Tipo de ruta	dorada verde
Access Rights	acceso abierto
Derechos de acceso	acceso abierto
Id de Web of Science	WOS:001117832600001
Identificador del recurso (Mandatado-único)	artículo de revisión
License	CC BY 4.0
Condición de la licencia (Recomendado-repetible)	CC BY 4.0
ISSN	1661-6596
Categoría WOS	Bioquímica y biología molecular Química
Referencia del Financiador (Mandatado si es aplicable-repetible)	UCT