Repositorio
Institucional

Antonini, Fernando

Klueppel, Leandro Eduardo

Olate, Sergio

Nascimento, Frederico Felipe

Albergaria-Barbosa, Jose Ricardo

Mazzonetto, Renato

Bone Repair is Influenced by Different Particle Sizes of Anorganic Bovine Bone Matrix: A Histologic and Radiographic Study In Vivo

LIPPINCOTT WILLIAMS & WILKINS

JOURNAL OF CRANIOFACIAL SURGERY

en

Purpose: The aim of this study was to analyze histologically and radiographically the influence of particle size of anorganic bovine bone matrix (ABBM) on bone repair. Materials and Methods: Four calvarial defects of 8 mm each were prepared in 18 adult New Zealand rabbits. The defects were then filled with either particulate autogenous bone (control group) or ABBM of large, medium, and small size granules. The animals were sacrificed at 15, 30, and 60 days after surgery. The samples were radiographically examined before being submitted to histological processing. Results: Autogenous bone showed a slight radiopacity at the beginning, which was increased at the final period, being very similar to the adjacent bone tissue. The large and medium size ABBM particles maintained the same radiographic behavior, showing a radiolucent area in the central portion of the defect at 60 days. ABBM of small size granules showed a slight radiolucity at the initial period, which was increased at the subsequent periods. More intense bone formation occurred in the control group (autogenous bone). All 3 particle sizes of the biomaterial resulted in inflammatory infiltration at 15 and 30 days. ABBM of small size granules lead to a greater amount of osteoid tissue, and the particles were almost totally reabsorbed within 60 days of implantation. Conclusions: Autogenous bone graft lead to the best result in terms of bone defect repair; ABBM of large and medium size granules are not totally reabsorbed at the observed period; ABBM of small size granules was more intensively reabsorbed and led to a greater osteoid tissue formation when compared to the medium and large ABBM granules.

Artículo original

The authors wish to thank Consulmat Company for kindly providing the biomaterial used for this research and the Campinas States University, Piracicaba School of Dentistry for supporting the study.

Los autores desean agradecer a la empresa Consulmat por proporcionar amablemente el biomaterial utilizado para esta investigación y a la Universidad Estatal de Campinas, Facultad de Odontología de Piracicaba, por apoyar el estudio.

10.1097/SCS.0b013e318286a0a3

pdf

Bone healing

bone graft

dental implant

ALVEOLAR RIDGE AUGMENTATION

FREEZE-DRIED BONE

AUTOGENOUS BONE

GRAFT SUBSTITUTES

DEFECTS

REGENERATION

IMPLANTS

Cicatrización ósea

injerto óseo

implante dental

AUMENTO DE LA CRESTA ALVEOLAR

HUESO LIOFILIZADO

HUESO AUTÓGENO

SUSTITUTOS DE INJERTOS

DEFECTOS

REGENERACIÓN

IMPLANTES

Bone healing

bone graft

dental implant

ALVEOLAR RIDGE AUGMENTATION

FREEZE-DRIED BONE

AUTOGENOUS BONE

GRAFT SUBSTITUTES

DEFECTS

REGENERATION

IMPLANTS

Cicatrización ósea

injerto óseo

implante dental

AUMENTO DE LA CRESTA ALVEOLAR

HUESO LIOFILIZADO

HUESO AUTÓGENO

SUSTITUTOS DE INJERTOS

DEFECTOS

REGENERACIÓN

IMPLANTES

Odontología, Cirugía y Medicina Oral

Biomateriales (Relacionados con implantes médicos, dispositivos y Sensores)

Anatomía y Morfología

Bone Repair is Influenced by Different Particle Sizes of Anorganic Bovine Bone Matrix: A Histologic and Radiographic Study In Vivo

JOURNAL OF CRANIOFACIAL SURGERY

hibrida

verde

metadata

metadata

PMID 23851743

en

Artículo original

versión publicada

Universidade Estadual de Campinas (UNICAMP), Piracicaba School of Dentistry

Universidade Estadual de Campinas (UNICAMP), Piracicaba School of Dentistry

LIPPINCOTT WILLIAMS & WILKINS

1049-2275

1074

1077

Cirugía

Surgery

pdf

WOS:000330129000057