Repositorio
Institucional

Yusuf, Salim

Corsi, Daniel J.

Subramanian, S. V.

Chow, Clara K.

Mckee, Martin

Chifamba, Jephat

Dagenais, Giles

Diaz, Rafael

Iqbal, Romaina

Kelishadi, Roya

Kruger, Annamarie

Lanas, Fernando

Lopez-Jaramilo, Patricio

Mony, Prem

Mohan, V.

Avezum, Alvaro

Oguz, Aytekin

Rahman, M. Omar

Rosengren, Annika

Szuba, Andrej

Li, Wei

Yusoff, Khalid

Yusufali, Afzalhussein

Rangarajan, Sumathy

Teo, Koon

Prospective Urban Rural Epidemiology (PURE) study: Baseline characteristics of the household sample and comparative analyses with national data in 17 countries

MOSBY-ELSEVIER

AMERICAN HEART JOURNAL

en

Background The PURE study was established to investigate associations between social, behavioural, genetic, and environmental factors and cardiovascular diseases in 17 countries. In this analysis we compare the age, sex, urban/rural, mortality, and educational profiles of the PURE participants to national statistics. Methods PURE employed a community-based sampling and recruitment strategy where urban and rural communities were selected within countries. Within communities, representative samples of adults aged 35 to 70 years and their household members (n = 424,921) were invited for participation. Results The PURE household population compared to national statistics had more women (sex ratio 95.1 men per 100 women vs 100.3) and was older (33.1 years vs 27.3), although age had a positive linear relationship between the two data sources (Pearson's r = 0.92). PURE was 59.3% urban compared to an average of 63.1% in participating countries. The distribution of education was less than 7% different for each category, although PURE households typically had higher levels of education. For example, 37.8% of PURE household members had completed secondary education compared to 31.3% in the national data. Age-adjusted annual mortality rates showed positive correlation for men (r = 0.91) and women (r = 0.92) but were lower in PURE compared to national statistics (7.9 per 1000 vs 8.7 for men; 6.7 vs 8.1 for women). Conclusions These findings indicate that modest differences exist between the PURE household population and national data for the indicators studied. These differences, however, are unlikely to have much influence on exposure-disease associations derived in PURE. Further, incidence estimates from PURE, stratified according to sex and/or urban/rural location will enable valid comparisons of the relative rates of various cardiovascular outcomes across countries.

Artículo original

S Yusuf is supported by the Mary W Burke endowed chair of the Heart and Stroke Foundation of Ontario. CK Chow is supported by a fellowship co-funded by the National Heart and Medical Research Council of Australia, National Heart Foundation of Australia, and Sydney Medical Foundation.The PURE study is funded by the Canadian Institutes of Health Research, Heart and Stroke Foundation of Ontario, and through unrestricted grants from several pharmaceutical companies [with major contributions from Astra Zeneca (Sweden and Canada), Novartis, Sanofi-Aventis(France and Canada), Boehringer Ingelheim (Germany & Canada), Servier, King Pharma, GSK], and additionally by various national bodies in different countries: Bangladesh: Independent University, Bangladesh, Mitra and Associates

Brazil: Unilever Health Institute, Brazil Canada: Public Health Agency of Canada and Champlain Cardiovascular Disease Prevention Network

Chile: Universidad de la Frontera

China: National Center for Cardiovascular Diseases

Colombia: Colciencias, Grant number: 6566-04-18062

India: Indian Council of Medical Research

Malaysia: Ministry of Science, Technology and Innovation of Malaysia: Grant Number 07-05-IFN-MEB010, Universiti Teknologi MARA, Universiti Kebangsaan Malaysia (UKM-Hejim-Komuniti-15-2010)

Poland: Polish Ministry of Science and Higher Education grant Nr 290/WPURE/2008/0, Wroclaw Medical University

South Africa: The North-West University, SANPAD (SA and Netherlands Programme for Alternative Development), National Research Foundation, Medical Research Council of SA, The SA Sugar Association (SASA), Faculty of Community and Health Sciences (UWC)

Sweden: Swedish Council for Working Life and Social Research, Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning, Swedish Heart and Lung Foundation, Swedish Research Council, Grant from the Swedish State under LUA Agreement, Grant from the Vastra Gotaland Region (FOUU)

TURKEY: Metabolic Syndrome Society, Astra Zeneca, Turkey, Sanofi Aventis, Turkey

UAE: Sheikh Hamdan Bin Rashid Al Maktoum Award For Medical Sciences, Dubai Health Authority, Dubai UAE.

S Yusuf cuenta con el apoyo de la cátedra Mary W Burke de la Fundación del Corazón y el Ictus de Ontario. CK Chow cuenta con el apoyo de una beca cofinanciada por el Consejo Nacional de Investigación Médica y Cardíaca de Australia, la Fundación Nacional del Corazón de Australia y la Fundación Médica de Sídney. El estudio PURE está financiado por los Institutos Canadienses de Investigación en Salud, la Fundación del Corazón y el Ictus de Ontario y mediante subvenciones sin restricciones de varias compañías farmacéuticas [con importantes contribuciones de Astra Zeneca (Suecia y Canadá), Novartis, Sanofi-Aventis (Francia y Canadá), Boehringer Ingelheim (Alemania y Canadá), Servier, King Pharma, GSK], y adicionalmente por varios organismos nacionales en diferentes países: Bangladesh: Independent University, Bangladesh, Mitra and Associates

Brasil: Unilever Health Institute, Brasil Canadá: Agencia de Salud Pública de Canadá y Champlain Cardiovascular Disease Prevention Network

Chile: Universidad de la Frontera

China: Centro Nacional de Enfermedades Cardiovasculares

Colombia: Colciencias, número de subvención: 6566-04-18062

India: Consejo Indio de Investigación Médica

Malasia: Ministerio de Ciencia, Tecnología e Innovación de Malasia: Subvención número 07-05-IFN-MEB010, Universiti Teknologi MARA, Universiti Kebangsaan Malaysia (UKM-Hejim-Komuniti-15-2010)

Polonia: Subvención del Ministerio de Ciencia y Educación Superior de Polonia n.º 290/WPURE/2008/0, Universidad Médica de Breslavia

Sudáfrica: Universidad del Noroeste, SANPAD (Programa de Sudáfrica y Países Bajos para el Desarrollo Alternativo), Fundación Nacional de Investigación, Consejo de Investigación Médica de Sudáfrica, Asociación Sudafricana del Azúcar (SASA), Facultad de Ciencias Comunitarias y de la Salud (UWC)

Suecia: Consejo Sueco para la Vida Laboral y la Investigación Social, Consejo Sueco de Investigación para el Medio Ambiente, las Ciencias Agrícolas y la Planificación Espacial, Fundación Sueca del Corazón y los Pulmones, Consejo Sueco de Investigación, Subvención del Estado Sueco en virtud del Acuerdo LUA, Subvención de la Región de Vastra Gotaland (FOUU)

TURQUÍA: Sociedad del Síndrome Metabólico, Astra Zeneca, Turquía, Sanofi Aventis, Turquía

EAU: Premio Sheikh Hamdan Bin Rashid Al Maktoum de Ciencias Médicas, Autoridad Sanitaria de Dubái, Dubái, EAU.

10.1016/j.ahj.2013.04.019

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Epidemiología

Salud Pública y Ambiental

Sistema Cardiovascular y Cardiaco

Prospective Urban Rural Epidemiology (PURE) study: Baseline characteristics of the household sample and comparative analyses with national data in 17 countries

AMERICAN HEART JOURNAL

hibrida

verde

metadata

metadata

PMID 24093842

en

Artículo original

versión publicada

MOSBY-ELSEVIER

0002-8703

636

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Sistemas cardíacos y cardiovasculares

Cardiac & Cardiovascular Systems

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