Repositorio
Institucional

Castro, Pablo

Verdejo, Hugo

Altamirano, Rodrigo

Downey, Patricio

Luis Vukasovic, Jose

Sepulveda, Luis

Lanas, Fernando

Bilbao, Paola

Pacheco, Ricardo

Rossel, Victor

Incidencia e importancia pronóstica del deterioro de la función renal en pacientes hospitalizados con insuficiencia cardiaca

Deterioration of kidney function as a risk factor for mortality among patients hospitalized for heart failure

SOC MEDICA SANTIAGO

REVISTA MEDICA DE CHILE

es

Background: Acute deterioration of kidney function among patients admitted to the hospital for cardiac failure is associated with an increased mortality. Aim: To investigate the association between deterioration of kidney function and mortality among patients hospitalized for cardiac failure. Material and Methods: Patients admitted for decompensated cardiac failure to 14 Chilean hospitals between 2002 and 2009 were incorporated to the study. Clinical and laboratory features were registered. Serum creatinine values on admission and discharge were determined. Hospital and long term mortality was determined requesting death certificates to the National Identification Service at the end of follow up, lasting 635 +/- 581 days. Results: One thousand sixty four patients were incorporated and 1100, aged 68 +/- 13 years (45% females) had information about renal function. Seventy seven percent were hypertensive and 36% were diabetic. Mean ejection fraction was 41 +/- 18% and 34% had an ejection fraction over 50%. Mean admission creatinine was 1.7 +/- 1.6 mg/dl and 19% had a creatinine over 2 mg/dl. Serum creatinine increased more than 0.5 mg/dl during hospitalization in 9% of general patients and in 11% of diabetics. The increase in creatinine was associated with a higher risk of hospital mortality (odds ratio (OR) 12.9, 95% confidence intervals (CI) 6.7-27.6) and long term mortality (OR 2.1, 95% CI 1.6-3). Conclusions: The deterioration of renal function during hospitalization of patients with heart failure is a risk factor for hospital and long term mortality.

Artículo original

10.4067/S0034-98872013000800005

pdf

Heart failure

Renal insufficiency

Risk factors

WORSENING RENAL-FUNCTION

SYSTOLIC DYSFUNCTION

SERUM CREATININE

OUTCOMES

IMPACT

ADMISSION

INSUFFICIENCY

CHALLENGE

SURVIVAL

TRIAL

Insuficiencia cardíaca

insuficiencia renal

factores de riesgo

EMPEORAMIENTO DE LA FUNCIÓN RENAL

DISFUNCIÓN SISTÓLICA

CREATININA SÉRICA

RESULTADOS

IMPACTO

INGRESO

INSUFICIENCIA

DESAFÍO

SUPERVIVENCIA

ENSAYO

Heart failure

Renal insufficiency

Risk factors

WORSENING RENAL-FUNCTION

SYSTOLIC DYSFUNCTION

SERUM CREATININE

OUTCOMES

IMPACT

ADMISSION

INSUFFICIENCY

CHALLENGE

SURVIVAL

TRIAL

Insuficiencia cardíaca

insuficiencia renal

factores de riesgo

EMPEORAMIENTO DE LA FUNCIÓN RENAL

DISFUNCIÓN SISTÓLICA

CREATININA SÉRICA

RESULTADOS

IMPACTO

INGRESO

INSUFICIENCIA

DESAFÍO

SUPERVIVENCIA

ENSAYO

Sistema Cardiovascular y Cardiaco

Urología y Nefrología

Medicina General e Interna

Incidencia e importancia pronóstica del deterioro de la función renal en pacientes hospitalizados con insuficiencia cardiaca

REVISTA MEDICA DE CHILE

dorada

verde

acceso abierto

CC BY

PMID 24448855

es

Artículo original

versión publicada

SOC MEDICA SANTIAGO

0034-9887

995

1002

Medicina general e interna

Medicine, General & Internal

pdf

WOS:000326301700005