Repositorio
Institucional

Schencke, Carolina

Salvo, Jessica

Vasconcellos, Adriana

del Sol, Mariano

Estudio Comparativo de la Cicatrización en Quemaduras con Tratamiento en Base a Miel de Ulmo (Eucryphia cordifolia) y Vitamina C oral versus Hidrogel en Cobayos (Cavia porcellus)

Comparative Study of Healing in Burns Treatment Based on Ulmo Honey (Eucryphia cordifolia) and Oral Vitamin C in Guinea Pig (Cavia porcellus) versus Hydrogel

SOC CHILENA ANATOMIA

INTERNATIONAL JOURNAL OF MORPHOLOGY

es

A burn is a traumatic injury resulting in local and systemic injury with oxidative changes. Honey has antioxidant, anti-inflammatory and antibacterial properties. At the same time, among other benefits vitamin C improves the epidermal barrier and reduces wound contraction. The aim of this study was to evaluate morphologically the effect of regimen with Ulmo honey + vitamin C in guinea pigs and compare its healing and debriding potential with Hydrogel + tull in injuries caused by type B burns at day 10 post-injury. We used 15 guinea pigs (Cavia porcellus) distributed in groups A (Ulmo honey and vitamin C topical, oral), B (hydrogel-tull), and control (0.9% saline). Wound debridement was observed daily and wound treatment was performed daily until biopsies were obtained at day 10 post-injury. Four 4 um sections were stained with HE, Masson's trichrome and PAS. In group A there was rapid debridement when compared with groups B and Control. Treatment study presented advanced proliferative phase at day 10 post-injury with vascularized tissue, and presence of collagen fibers and fibroblasts. The epidermis was completely regenerated, presenting a visible basal lamina by PAS staining. Group B presented an initial proliferative fibroblastic phase, showing acute dermal elements. Epithelialization phase was completed in only 50% of the samples. Ulmo honey + vitamin C substances have been shown to be effective as treatment material in healing of type B burns in guinea pig skin.

Artículo original

10.4067/S0717-95022013000300010

pdf

Healing

Honey

Vitamin C

Burns

Curación

Miel

Vitamina C

Quemaduras

Healing

Honey

Vitamin C

Burns

Curación

Miel

Vitamina C

Quemaduras

Biotecnología Relacionada con la Salud

Anatomía y Morfología

Cirugía

Estudio Comparativo de la Cicatrización en Quemaduras con Tratamiento en Base a Miel de Ulmo (Eucryphia cordifolia) y Vitamina C oral versus Hidrogel en Cobayos (Cavia porcellus)

INTERNATIONAL JOURNAL OF MORPHOLOGY

dorada

verde

acceso abierto

acceso abierto

CC BY-NC

es

Artículo original

versión publicada

SOC CHILENA ANATOMIA

0717-9502

839

844

Anatomía y morfología

Anatomy & Morphology

pdf

WOS:000327821700010