Repositorio UFRO · Omeka S

Application of a Low-Level Laser Therapy and the Purified Protein from Natural Latex (Hevea brasiliensis) in the Controlled Crush Injury of the Sciatic Nerve of Rats: A Morphological, Quantitative, and Ultrastructural Study

Primer Autor	Watanabe, Ii-sei
Co-autores	Dias, Fernando Jose Mardegan Issa, Joao Paulo Iyomasa, Mamie Mizusaki Coutinho-Netto, Joaquim Junqueria Calzzani, Ricardo Alexandre Iyomasa, Daniela Mizusaki Sousa, Luiz Gustavo Yokomizo de Almeida, Sonia Regina Cury, Diego Pulzatto
Título	Application of a Low-Level Laser Therapy and the Purified Protein from Natural Latex (Hevea brasiliensis) in the Controlled Crush Injury of the Sciatic Nerve of Rats: A Morphological, Quantitative, and Ultrastructural Study
Editorial	HINDAWI LTD
Revista	BIOMED RESEARCH INTERNATIONAL
Lenguaje	en
Resumen	This study analyzed the effects of a low-level laser therapy (LLLT, 15 J/cm(2), 780 nm wavelength) and the natural latex protein (P1, 0.1%) in sciatic nerve after crush injury (15 Kgf, axonotmesis) in rats. Sixty rats (male, 250 g) were allocated into the 6 groups (n = 10): CG-control group; EG-nerve exposed; IG-injured nerve without treatment; LG-crushed nerve treated with LLLT; PG-injured nerve treated with P1; and LPG-injured nerve treated with LLLT and P1. After 4 or 8 weeks, the nerve samples were processed for morphological, histological quantification and ultrastructural analysis. After 4 weeks, the myelin density and morphological characteristics improved in groups LG, PG, and LPG compared to IG. After 8 weeks, PG, and LPG were similar to CG and the capillary density was higher in the LG, PG, and LPG. In the ultrastructural analysis the PG and LPG had characteristics that were similar to the CG. The application of LLLT and/or P1 improved the recovery from the nerve crush injury, and in the long term, the P1 protein was the better treatment used, since only the application of LLLT has not reached the same results, and these treatments applied together did not potentiate the recovery.
Tipo de Recurso	Artículo original
Description	The authors would like to thank FAPESP for financial support of this study. Los autores desean agradecer a FAPESP por el apoyo financiero brindado para este estudio.
doi	10.1155/2013/597863
Formato Recurso	pdf
Palabras Claves	PERIPHERAL-NERVE MYELIN REGENERATION 780 NM PHOTOTHERAPY RECOVERY REPAIR LONG TISSUE NERVIOS PERIFÉRICOS REGENERACIÓN DE MIELINA 780 NM FOTOTERAPIA RECUPERACIÓN REPARACIÓN LARGO TEJIDO
Ubicación del archivo	http://dx.doi.org/10.1155/2013/597863
Materias	PERIPHERAL-NERVE MYELIN REGENERATION 780 NM PHOTOTHERAPY RECOVERY REPAIR LONG TISSUE NERVIOS PERIFÉRICOS REGENERACIÓN DE MIELINA 780 NM FOTOTERAPIA RECUPERACIÓN REPARACIÓN LARGO TEJIDO
Disciplinas de la OCDE	Anatomía y Morfología Neurociencias Otros Temas de Medicina Básica
Título de la cita (Recomendado-único)	Application of a Low-Level Laser Therapy and the Purified Protein from Natural Latex (Hevea brasiliensis) in the Controlled Crush Injury of the Sciatic Nerve of Rats: A Morphological, Quantitative, and Ultrastructural Study
Revista/Libro	BIOMED RESEARCH INTERNATIONAL
Tipo de ruta	dorada verde
Access Rights	acceso abierto
Derechos de acceso	acceso abierto
License	CC BY 4.0
Condición de la licencia (Recomendado-repetible)	CC BY 4.0
Identificador alternativo	PMID 23936823
Idioma	en
Identificador del recurso (Mandatado-único)	Artículo original
Versión del recurso (Recomendado-único)	versión publicada
Entidad financiadora	FAPESP
Referencia del Financiador (Mandatado si es aplicable-repetible)	FAPESP
Editorial	HINDAWI LTD
ISSN	2314-6133
Página de inicio (Recomendado-único)	597863
Categoría WOS	Biotecnología y Microbiología Aplicada Medicina, Investigación y Experimentación Biotechnology & Applied Microbiology Medicine, Research & Experimental
Formato	pdf
Id de Web of Science	WOS:000321859700001