Growth Factors Included in Terminologia Embryologica: Critical Analysis

Primer Autor
Conei, Daniel
Co-autores
Rojas, Mariana
Título
Growth Factors Included in Terminologia Embryologica: Critical Analysis
Editorial
SOC CHILENA ANATOMIA
Revista
INTERNATIONAL JOURNAL OF MORPHOLOGY
Lenguaje
en
Resumen
"Each term included in Terminologia Embryologica (TE), published in 2013 and with a second edition in 2017 subject to approval by the Federative International Programme For Anatomical Terminology (FIPAT), must be structured based on its principles: Names must have an informative value, eponyms, homonyms and concordant names are deleted. However, this does not happen in some terms. That is why the terms included in the section ""Growth Factors"" (Factores crescentiae, E.4.0.1.0.0.0.1) were analyzed in the way they are presented, their concordance with what was published in reviews of PubMed database, and their naming form was described based on what was used by the Genes Nomenclature Committee of the Human Genome Organisation (HGNC). It was evidenced that in the terms Family Hedgehog (Familia erinacea, E.4.0.1.0.0.0.6) and Superfamily of the Epidermal Growth Factor (EGF) (Superfamilia factoris epidermalis)[EGF] crescentiae, E.4.0.1.0.0.0.10) these do not agree with the classification proposed by TE based on the receiver that is involved in the activity of the growth factor, since in the case of Hedgehog family not only does the patched receptor participate, but the smoothened one does as well. In EGF there is tyrosine kinase receptor activity and not serine/threonine kinase, as presented in the official document. Also, the ligands fibronectin/laminin and delta/serrate appear as growth factors, despite not being catalogued as such. Furthermore, oftentimes the way in which such terms are constructed is contrary to the FIPAT presentation, but follows the HGNC line of work that holds the HGNC."
Tipo de Recurso
Artículo original
doi
10.4067/S0717-95022018000200500
Formato Recurso
pdf
Palabras Claves
Terminologia Embryologica# Growth Factors# Hedgehog Family# Epidermal Growth Factor Superfamily# Ligand# HUGO Gene Nomenclature Committee
Ubicación del archivo
http://dx.doi.org/10.4067/S0717-95022018000200500
Categoría OCDE
Anatomy & Morphology
Materias
Terminología embriológica# Factores de Crecimiento# Familia de erizos# Superfamilia del factor de crecimiento epidérmico# ligando# Comité de nomenclatura genética de HUGO
Disciplinas de la OCDE
Genética y Herencia
Biología Molecular
Bioquímica
Id de Web of Science
WOS:000438815300021
Título de la cita (Recomendado-único)
Growth Factors Included in <i>Terminologia Embryologica</i>: Critical Analysis
Identificador del recurso (Mandatado-único)
Artículo original
Versión del recurso (Recomendado-único)
version publicada
Editorial
SOC CHILENA ANATOMIA
Revista/Libro
INTERNATIONAL JOURNAL OF MORPHOLOGY
Categoría WOS
Anatomía y Morfología
ISSN
0717-9502
Idioma
en
Formato
pdf
Tipo de ruta
dorada#verde
Access Rights
acceso abierto
Derechos de acceso
acceso abierto
License
CC BY-NC
Página de inicio (Recomendado-único)
233
Página final (Recomendado-único)
244
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