Repositorio
Institucional

Risopatron, J.

Merino, O.#Gregorio, B.#Sampaio, F.#Sanchez, R.

Role of Vitamin D in the Development of Obesity

SOC CHILENA ANATOMIA

INTERNATIONAL JOURNAL OF MORPHOLOGY

en

Antecedents in the literature suggest that vitamin D (VD) play a role in overweigh/obesity. The present study evaluated the effect of VD deficiency diet intake and fat hight on overweight/obesity about white adipose tissue (WAT) and body mass (BM) gain. Animals were divided into four experimental groups according to the lipid and VD content of their diets, G1: CVD+ (C: control diet with VD+, n=5), G2: CVD-(control diet without VD-, n=5), G3: HFVD+ (high fat diet, with VD+, n=5), G4: HFVD-(HF diet without VD-, n=5). The diets were administered for three months and BW was monitored weekly. At the end of this period all animals were euthanized. Epididymal (EFM), retroperitoneal (RFM) and subcutaneous (SFM) fat mass were removed, weighted. At 12 weeks the body mass of the animals that were fed without VD-diets, G2: 507.60 +/- 17.31 g, and G4: 528.50 +/- 13.50 g were significantly higher (p < 0.05), than the counterparts G1: 485.0 +/- 11.29 g and G3: 521.20 +/- 26.20 g respectively. Similarly, the animals fed with VD-diets had a greater EFM and SFM (p < 0.05) compared with the respective controls (VD+). Nevertheless, the animals fed with high fat diet had equal RFM (G3: 12.2 +/- 4.10 g, G4: 12.88 +/- 2.3 g, p > 0.05). The results demonstrate that the nutrition of rats with diet deficient in VD and high fat, promotes overweight by increasing fat deposits, suggestion a cause-effect relationship between VD deficiency and overweight. These results suggest that VD deficiency increases the risk of visceral fat obesity in males.

Artículo original

This work was supported by the FAPERJ/UFRO NoFPJ 15-0014, CONICYT-PFCHA / National Doctorate Program /2015-21151103. The authors are grateful to CEMyQ and CEBIOR. University of La Frontera, Temuco. Chile.

Este trabajo contó con el apoyo de FAPERJ/UFRO NoFPJ 15-0014, CONICYT-PFCHA / Programa Nacional de Doctorado /2015-21151103. Los autores agradecen al CEMyQ y al CEBIOR. Universidad de La Frontera, Temuco, Chile.

10.4067/S0717-95022017000401568

pdf

VD deficiency# Gain weight# Fat gain# Fat pad# Visceral fat obesity

http://dx.doi.org/10.4067/S0717-95022017000401568

Anatomy & Morphology

deficiencia de VD# Aumentar de peso# Aumento de grasa# Almohadilla grasa# Obesidad grasa visceral

Ciencia Animal y lechería

Nutrición y Dietética

Endocrinología y Metabolismo (Incluye Diabetes, Hormonas)

WOS:000428048400057

Role of Vitamin D in the Development of Obesity

Artículo original

version publicada

SOC CHILENA ANATOMIA

INTERNATIONAL JOURNAL OF MORPHOLOGY

Anatomía y Morfología

0717-9502

en

FAPERJ/UFRO FPJ 15-0014#ANID CONICYT 21151103#UFRO CEBIOR

FAPERJ/UFRO FPJ 15-0014

ANID CONICYT-PFCHA /National Doctorate Program 2015-21151103

This work was supported by the FAPERJ/UFRO NoFPJ 15-0014, CONICYT-PFCHA / National Doctorate Program /2015-21151103. The authors are grateful to CEMyQ and CEBIOR. University of La Frontera, Temuco. Chile.

pdf

dorada#verde

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acceso abierto

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