Repositorio
Institucional

Casanova, Jean-Laurent

Boisson-Dupuis, Stephanie

Ramirez-Alejo, Noe

Li, Zhi

Patin, Etienne

Rao, Geetha

Kerner, Gaspard

Lim, Che Kang

Krementsov, Dimitry N.

Hernandez, Nicholas

Ma, Cindy S.

Zhang, Qian

Markle, Janet

Martinez-Barricarte, Ruben

Payne, Kathryn

Fisch, Robert

Deswarte, Caroline

Halpern, Joshua

Bouaziz, Matthieu

Mulwa, Jeanette

Sivanesan, Durga

Lazarov, Tomi

Naves, Rodrigo

Garcia, Patricia

Itan, Yuval

Boisson, Bertrand

Checchi, Alix

Jabot-Hanin, Fabienne

Cobat, Aurelie

Guennoun, Andrea

Jackson, Carolyn C.

Pekcan, Sevgi

Caliskaner, Zafer

Inostroza, Jaime

Costa-Carvalho, Beatriz Tavares

Tavares de Albuquerque, Jose Antonio

Garcia-Ortiz, Humberto

Orozco, Lorena

Ozcelik, Tayfun

Abid, Ahmed

Rhorfi, Ismail Abderahmani

Souhi, Hicham

Amrani, Hicham Naji

Zegmout, Adil

Geissmann, Frederic

Michnick, Stephen W.

Muller-Fleckenstein, Ingrid

Fleckenstein, Bernhard

Puel, Anne

Ciancanelli, Michael J.

Marr, Nico

Abolhassani, Hassan

Elvira Balcells, Maria

Condino-Neto, Antonio

Strickler, Alexis

Abarca, Katia

Teuscher, Cory

Ochs, Hans D.

Reisli, Ismail

Sayar, Esra H.

El-Baghdadi, Jamila

Bustamante, Jacinta

Hammarstrom, Lennart

Tangye, Stuart G.

Pellegrini, Sandra

Quintana-Murci, Lluis

Abel, Laurent

Tuberculosis and impaired IL-23-dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant

AMER ASSOC ADVANCEMENT SCIENCE

SCIENCE IMMUNOLOGY

English

artículo original

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The Laboratory of Human Genetics of Infectious Diseases was supported, in part, by grants from the French National Agency for Research (ANR) under the Investissement d'avenir program (grant no. ANR-10-IAHU-01), the TBPATHGEN project (grant no. ANR-14-CE14-0007-01), the GENMSMD project (grant no. ANR-16-CE17-0005-01), the Integrative Biology of Emerging Infectious Diseases Laboratory of Excellence (grant no. ANR-10-LABX-62-IBEID), the European Research Council (ERC; grant no. ERC-2010-AdG-268777), the SCOR Corporate Foundation for Science, the St. Giles Foundation, the National Center for Research Resources and the National Center for Advancing Sciences (NCATS), NIH (grant no. UL1TR001866), the National Institute of Allergy and Infectious Diseases (NIAID) (grant nos. 5R01AI089970, 5R37AI095983, 5U01AI088685, and 5U19AI111143), and The Rockefeller University. Work at the Cytokine Signaling Unit was supported, in part, by a grant from Fondation de la Recherche Medicale to S. Pellegrini (grant no. DEQ20170336741). J.B. was supported by Support of Clinical Research (grant no. SRC2017). C.S.M. and S.G.T. were supported by fellowships and grants from the National Health and Medical Research Council of Australia and the Office of Health and Medical Research of the Government of New South Wales (Australia). M.E.B. was supported by Fondo Nacional de Desarrollo Cientifico y Tecnologico (FONDECYT; grant no. 1171570) A.C.-N. was supported by Fundacao de Amparo a Pesquisa do Estado e de Sao Paulo (Fapesp) and Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq). N.R.-A. was supported by fellowships from Consejo Nacional de Ciencia y Tecnologia (CONACYT; grant no. 264011) and the Stony Wold-Herbert Fund. Z.L. was supported by the CNRS. J. Markle was supported by the Charles H. Revson Senior Fellowship in Biomedical Sciences and NIAID grant K99AI27932. C.C.J. was the Damon Runyon-Richard Lumsden Foundation Physician Scientist supported by the Damon Runyon Cancer Research Foundation (PST-03-15). H.D.O. was supported by the Jeffrey Modell Foundation. N.H. was supported by a Medical Scientist Training Program grant from the National Institute of General Medical Sciences of the NIH under award no. T32GM007739 to the Weill Cornell/Rockefeller/Sloan-Kettering Tri-Institutional MD-PhD Program. The content of this study is the sole responsibility of the authors and does not necessarily represent the official views of the NIH. The Yale Center for Mendelian Genomics (UM1HG006504) is funded by the National Human Genome Research Institute. Funds were also provided by the National Heart, Lung, and Blood Institute. The GSP Coordinating Center (U24 HG008956) contributed to cross-program scientific initiatives and provided logistical and general study coordination.

10.1126/sciimmunol.aau8714

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Inmunología

Genética y Herencia

Enfermedades Infecciosas

WOS:000455005400004

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Tuberculosis and impaired IL-23-dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant

artículo original

version publicada

2470-9468

suscripción